分辨率为7埃的噬菌体阻遏物-操纵基因复合物。
A phage repressor-operator complex at 7 A resolution.
作者信息
Anderson J E, Ptashne M, Harrison S C
出版信息
Nature. 1985;316(6029):596-601. doi: 10.1038/316596a0.
DOI:10.1038/316596a0
PMID:4033757
Abstract
The crystal structure of a complex between the DNA-binding domain of phage 434 repressor and a synthetic 434 operator shows that the protein, very similar in conformation to gamma repressor, binds to B-form DNA with the second alpha-helix of a helix-turn-helix motif lying in the major groove.
摘要
噬菌体434阻遏物的DNA结合结构域与合成的434操纵基因之间复合物的晶体结构表明，该蛋白质在构象上与γ阻遏物非常相似，其螺旋-转角-螺旋基序的第二个α螺旋位于大沟中，与B型DNA结合。
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