Parker Alison E, Scull Tracy M, Green Jada, Stump Kathryn N
J Pediatr Health Care. 2025 May-Jun;39(3):335-345. doi: 10.1016/j.pedhc.2024.10.013. Epub 2025 May 8.
Pediatric clinical trials are important for advancing treatments for youth; however, recruitment remains a challenge. This study examines the effectiveness of DigiKnowIt News, a website designed to educate adolescents about clinical trials.
Parent-adolescent pairs were randomly assigned to intervention (N = 83) or wait-list control (N = 96) groups. Pairs completed online pretest and posttest questionnaires related to knowledge and attitudes about research.
Adolescents and parents in the intervention group, compared to the wait-list control, significantly increased in their familiarity with and positive attitudes toward clinical trials. Adolescents improved in their confidence for participating in clinical trials. Promising findings emerged with marginal increases in positive beliefs about clinical trials and likelihood of allowing an adolescent to participate. Participants reported high levels of satisfaction with DigiKnowIt News.
Providing adolescents and parents with information in fun, interactive, and engaging ways can inform their decision-making about clinical trials.
儿科临床试验对于推进青少年治疗方法至关重要；然而，招募受试者仍然是一项挑战。本研究考察了DigiKnowIt News网站的有效性，该网站旨在教育青少年了解临床试验。
将父母-青少年对随机分配至干预组（N = 83）或等待名单对照组（N = 96）。这些对子完成了与研究知识和态度相关的在线预测试和后测试问卷。
与等待名单对照组相比，干预组的青少年和父母对临床试验的熟悉程度和积极态度显著提高。青少年参与临床试验的信心有所增强。关于临床试验的积极信念和允许青少年参与的可能性略有增加，出现了有前景的结果。参与者对DigiKnowIt News网站满意度很高。
以有趣、互动和引人入胜的方式为青少年和父母提供信息，可以为他们关于临床试验的决策提供参考。
