Sage J I, Weinstein M P, Miller D C
Neurology. 1985 Oct;35(10):1470-2. doi: 10.1212/wnl.35.10.1470.
Two patients had clinical findings of encephalopathy that progressed in 4 to 5 months. One patient had headache, fatigue, lethargy, hemiparesis, and a seizure. The second patient had only forgetfulness, confusion, and lethargy without focal signs. Herpes simplex virus was grown from brain biopsy in the first patient and from CSF in the second patient. These cases suggest that herpes simplex virus caused the encephalitis and that it should be considered in the differential diagnosis of chronic encephalopathy.
两名患者出现脑病的临床症状，在4至5个月内病情进展。一名患者有头痛、疲劳、嗜睡、偏瘫和癫痫发作。第二名患者仅有健忘、意识模糊和嗜睡，无局灶性体征。在第一名患者的脑活检组织中培养出单纯疱疹病毒，在第二名患者的脑脊液中培养出该病毒。这些病例表明，单纯疱疹病毒导致了脑炎，在慢性脑病的鉴别诊断中应考虑到该病毒。
