Silberstein P
Med J Aust. 1977 Jan 22;1(4):95, 98-9. doi: 10.5694/j.1326-5377.1977.tb130532.x.
An uncontrolled trial of sodium valproate in 25 severe epileptics uncontrollable by conventional antiepileptic drugs is presented. Excellent control was achieved in petit mal, myoclonic and minor motor seizures. No serious side effects were encountered, but hyperactivity may be aggravated and interaction with other anticonvulsants does occur.
本文介绍了一项针对25名使用传统抗癫痫药物无法控制病情的严重癫痫患者进行的丙戊酸钠非对照试验。在失神发作、肌阵挛发作和轻微运动性发作方面实现了良好控制。未出现严重副作用,但多动可能会加重,并且确实会与其他抗惊厥药发生相互作用。