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一名自述患有海湾战争综合症的退伍军人的精神问题处理:病例报告

Navigating Psychiatric Concerns in a Veteran Reporting Gulf War Illness: A Case Report.

作者信息

Botz-Zapp Christian Alan, Wang Jami, Kazangian Eric, Ferrer Jennifer

机构信息

Kaiser Permanente Bernard J Tyson School of Medicine, Pasadena, CA, USA.

Kaiser Permanente Southern California, Fontana, CA, USA.

出版信息

Perm J. 2025 Jun 16;29(2):84-87. doi: 10.7812/TPP/24.071. Epub 2025 May 9.

DOI:10.7812/TPP/24.071
PMID:40340723
Abstract

Gulf War illness (GWI) is a chronic condition affecting nearly a third of Gulf War veterans and is characterized by persistent symptoms across a number of physical and neuropsychiatric domains. This case study examined a 52-year-old veteran admitted on a psychiatric hold for danger to others. The patient's symptoms, including chronic migraine, widespread musculoskeletal pain, skin sensitivities, environmental allergies, and mood and cognitive disturbances, met criteria for GWI according to 2 accepted case definitions. Initial misdiagnosis of psychosis was corrected upon evaluation, which identified severe anxiety consistent with generalized anxiety disorder. Treatment focused on providing validation of the patient's chronic symptoms and managing his anxiety through pharmacologic intervention. This case underscored the importance of recognizing GWI to ensure accurate diagnoses and targeted care for veterans.

摘要

海湾战争综合征(GWI)是一种慢性病,影响了近三分之一的海湾战争退伍军人,其特征是在多个身体和神经精神领域存在持续症状。本案例研究考察了一名52岁因对他人构成危险而被强制进行精神治疗的退伍军人。根据两种公认的病例定义,该患者的症状,包括慢性偏头痛、广泛的肌肉骨骼疼痛、皮肤敏感、环境过敏以及情绪和认知障碍,符合海湾战争综合征的标准。经评估,最初对精神病的误诊得到纠正,确诊为与广泛性焦虑症相符的严重焦虑症。治疗重点是确认患者的慢性症状,并通过药物干预来控制其焦虑情绪。该案例强调了识别海湾战争综合征对于确保退伍军人得到准确诊断和针对性治疗的重要性。

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本文引用的文献

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Mitochondria in depression: The dysfunction of mitochondrial energy metabolism and quality control systems.抑郁症中的线粒体:线粒体能量代谢和质量控制系统的功能障碍。
CNS Neurosci Ther. 2024 Feb;30(2):e14576. doi: 10.1111/cns.14576.
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Adverse effect propensity: A new feature of Gulf War illness predicted by environmental exposures.不良反应倾向:由环境暴露预测的海湾战争综合征的一个新特征。
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Mitochondrial impairment but not peripheral inflammation predicts greater Gulf War illness severity.
线粒体损伤而非外周炎症可预测海湾战争病严重程度更高。
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7
Acetylcholinesterase inhibitor exposures as an initiating factor in the development of Gulf War Illness, a chronic neuroimmune disorder in deployed veterans.乙酰胆碱酯酶抑制剂暴露可作为海湾战争疾病(一种在部署的退伍军人中发生的慢性神经免疫疾病)发展的起始因素。
Neuropharmacology. 2020 Jul;171:108073. doi: 10.1016/j.neuropharm.2020.108073. Epub 2020 Apr 2.
8
Gulf War Illness-associated increases in blood levels of interleukin 6 and C-reactive protein: biomarker evidence of inflammation.海湾战争综合症相关的白细胞介素6和C反应蛋白血液水平升高:炎症的生物标志物证据。
BMC Res Notes. 2019 Dec 18;12(1):816. doi: 10.1186/s13104-019-4855-2.
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Helpful ways providers can communicate about persistent medically unexplained physical symptoms.有助于提供者沟通持续性医学无法解释的身体症状的方法。
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10
Blood Biomarkers of Chronic Inflammation in Gulf War Illness.海湾战争综合征中慢性炎症的血液生物标志物
PLoS One. 2016 Jun 28;11(6):e0157855. doi: 10.1371/journal.pone.0157855. eCollection 2016.