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载银金纳米颗粒的树脂类根管封闭剂的推出粘结强度:体外研究

Push out bond strength of resin -based endodontic sealer loaded with silver gold nanoparticles in vitro study.

作者信息

Hassan Nermine, Riad Mona, Ibrahim Shereen Hafez, Abulnoor Bassam Ahmed, Hassan Reham

机构信息

Lecturer of Endodontics, Faculty of Dentistry, Cairo University, Giza, Egypt.

Professor of Conservative Dentistry, Faculty of Dentistry, Cairo University, Giza, Egypt.

出版信息

BDJ Open. 2025 May 8;11(1):47. doi: 10.1038/s41405-025-00331-x.

Abstract

OBJECTIVES

The push-out bond strength to the intraradicular dentin was evaluated in this in vitro study using an epoxy-based endodontic sealer loaded with silver-gold nanoparticles. Additionally, the benefits of using the nanoparticles as a canal pretreatment before applying the sealer were evaluated in comparison to using the sealer alone.

METHODOLOGY

After being decoronated and instrumented, thirty extracted human central incisors were obturated and then divided horizontally into three parts (coronal, middle, and apical) with a thickness of 2 mm. Three groups of slices were created at random: Groups I (control) and II received AH Plus sealer, AH Plus sealer loaded with silver gold nanoparticles, and III received nanoparticles as a pretreatment for the canal prior to gutta-percha and AH Plus sealer for obturation. The specimens were loaded at a rate of 0.5 mm/min utilizing a Universal Test Machine and put through a push-out test. Statistics were applied to each data collection. Additionally, the significance level was set at P ≤ 0.05.

RESULTS

A push-out test showed that the groups differed significantly from one another. The tested groups differed significantly in both the coronal and middle portions, with group (II) exhibiting the highest push-out strength values. Group (II) had the highest push-out strength values in the apical portion (3.66 ± 0.72), followed by group (III) (2.90 ± 1.45), while group (I) had the lowest value (2.88 ± 1.73). There was no significant difference between the groups.

CONCLUSIONS

the experimental AH Plus sealer combined with silver-gold nanoparticles demonstrated the most effective adhesion followed by nanoparticles as a canal pretreatment prior to sealer application when compared to AH Plus sealer alone.

摘要

目的

在本体外研究中,使用负载银金纳米颗粒的环氧类根管封闭剂评估其与根管内牙本质的推出粘结强度。此外,与单独使用封闭剂相比,评估了在应用封闭剂之前使用纳米颗粒进行根管预处理的益处。

方法

30颗拔除的人上颌中切牙在去冠和预备后进行充填,然后水平切成厚度为2毫米的三个部分(冠部、中部和根尖部)。随机分为三组切片:第一组(对照组)和第二组分别使用AH Plus封闭剂、负载银金纳米颗粒的AH Plus封闭剂,第三组在根管内使用纳米颗粒进行预处理,然后用牙胶和AH Plus封闭剂进行充填。使用万能试验机以0.5毫米/分钟的速率加载标本,并进行推出试验。对每个数据收集进行统计分析。此外,显著性水平设定为P≤0.05。

结果

推出试验表明,各组之间存在显著差异。测试组在冠部和中部均有显著差异,第二组表现出最高的推出强度值。第二组在根尖部的推出强度值最高(3.66±0.72),其次是第三组(2.90±1.45),而第一组的值最低(2.88±1.73)。各组之间无显著差异。

结论

与单独使用AH Plus封闭剂相比,实验性的AH Plus封闭剂与银金纳米颗粒结合表现出最有效的粘结力,其次是在应用封闭剂之前使用纳米颗粒进行根管预处理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/17ae/12062364/9693d3695134/41405_2025_331_Fig1_HTML.jpg

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