Yilmaz Abdurrahim, Gem Kadir, Kalebasi Mucahit, Varol Rahmetullah, Gencoglan Zuhtu Oner, Samoylenko Yegor, Tosyali Hakan Koray, Okcu Guvenir, Uvet Huseyin
Division of Systems Medicine, Department of Metabolism, Digestion, and Reproduction, Imperial College London, London, SW7 2AZ, UK.
Department of Orthopedics and Traumatology, Manisa Alasehir State Hospital, 45600, Manisa, Turkey.
Sci Rep. 2025 May 8;15(1):16001. doi: 10.1038/s41598-025-98852-w.
Accurate diagnosis of orthopedic injuries, especially pelvic and hip fractures, is vital in trauma management. While pelvic radiographs (PXRs) are widely used, misdiagnosis is common. This study proposes an automated system that uses convolutional neural networks (CNNs) to detect potential fracture areas and predict fracture conditions, aiming to outperform traditional object detection-based systems. We developed two deep learning models for hip fracture detection and prediction, trained on PXRs from three hospitals. The first model utilized automated hip area detection, cropping, and classification of the resulting patches. The images were preprocessed using the Contrast Limited Adaptive Histogram Equalization (CLAHE) algorithm. The YOLOv5 architecture was employed for the object detection model, while three different pre-trained deep neural network (DNN) architectures were used for classification, applying transfer learning. Their performance was evaluated on a test dataset, and compared with 35 clinicians. YOLOv5 achieved a 92.66% accuracy on regular images and 88.89% on CLAHE-enhanced images. The classifier models, MobileNetV2, Xception, and InceptionResNetV2, achieved accuracies between 94.66% and 97.67%. In contrast, the clinicians demonstrated a mean accuracy of 84.53% and longer prediction durations. The DNN models showed significantly better accuracy and speed compared to human evaluators (p < 0.0005, p < 0.01). These DNN models highlight promising utility in trauma diagnosis due to their high accuracy and speed. Integrating such systems into clinical practices may enhance the diagnostic efficiency of PXRs.
准确诊断骨科损伤,尤其是骨盆和髋部骨折,在创伤管理中至关重要。虽然骨盆X光片(PXR)被广泛使用,但误诊很常见。本研究提出了一种自动化系统,该系统使用卷积神经网络(CNN)来检测潜在骨折区域并预测骨折情况,旨在超越传统的基于目标检测的系统。我们开发了两个用于髋部骨折检测和预测的深度学习模型,在来自三家医院的PXR上进行训练。第一个模型利用自动髋部区域检测、裁剪以及对所得图像块进行分类。使用对比度受限自适应直方图均衡化(CLAHE)算法对图像进行预处理。目标检测模型采用YOLOv5架构,而分类则使用三种不同的预训练深度神经网络(DNN)架构,并应用迁移学习。在测试数据集上评估了它们的性能,并与35名临床医生进行了比较。YOLOv5在常规图像上的准确率达到92.66%,在CLAHE增强图像上的准确率为88.89%。分类器模型MobileNetV2、Xception和InceptionResNetV2的准确率在94.66%至97.67%之间。相比之下,临床医生的平均准确率为84.53%,预测时间更长。与人类评估者相比,DNN模型显示出显著更高的准确率和速度(p < 0.0005,p < 0.01)。这些DNN模型因其高准确率和速度,在创伤诊断中显示出有前景的实用性。将此类系统整合到临床实践中可能会提高PXR的诊断效率。