超重/肥胖的2型糖尿病患者饮用绿茶与心血管疾病发病率的关系：一项基于社区的队列研究
Green tea consumption and incidence of cardiovascular disease in type 2 diabetic patients with overweight/obesity: a community-based cohort study.
作者信息
Liu Bingyue, Gu Shujun, Zhang Jin, Zhou Hui, Su Jian, Wang Sudan, Sun Qian, Zhou Zhengyuan, Zhou Jinyi, Dong Chen
机构信息
Department of Epidemiology and Statistics, School of Public Health, Medical College of Soochow University, Soochow, Jiangsu, China.
Suzhou Changshu Centers for Disease Control and Prevention, Soochow, China.
出版信息
Arch Public Health. 2024 Feb 2;82(1):18. doi: 10.1186/s13690-024-01242-3.
BACKGROUND
Green tea has been reported to be potentially protective against the development of cardiovascular disease (CVD). This study aimed to investigate the association between green tea consumption and incident CVD in type 2 diabetes (T2D) patients with overweight/obesity.
METHODS
A total of 4756 Chinese overweight/obese T2D patients were recruited and followed up for 6.27 years. Information on green tea consumption was collected at baseline using interviewer-administered questionnaires. Hazard ratios (HRs) and 95% confidence intervals (CIs) for incident CVD according to green tea consumption were estimated using the Cox proportional hazards model.
RESULTS
Compared with non-habitual consumers, participants who consumed > 5 g/day of green tea leaves reduced the risk of CVD by 29% (95%CI: 0.55-0.92), stroke by 30% (95%CI: 0.51-0.95) and coronary heart disease (CHD) by 40% (95%CI: 0.40-0.89). Similarly, participants who consumed green tea for ≥ 40 years reduced the risk of CVD by 31% (95%CI: 0.54-0.88), stroke by 33% (95%CI: 0.50-0.90) and CHD by 39% (95%CI: 0.42-0.88). Among participants with < 5-year history of T2D, > 5 g/day of tea leaves and > 40 years of tea consumption were associated with 59% (95%CI: 0.23-0.72) and 57% (95%CI: 0.26-0.74) reduced risk of stroke, respectively. However, among participants with ≥ 5-year history of T2D, > 5 g/day of tea leaves and > 40 years of tea consumption were associated with a 50% (95%CI: 0.30-0.82) and 46% (95%CI: 0.35-0.85) reduced risk of CHD, respectively.
CONCLUSIONS
Green tea consumption is associated with reduced risk of CVD, stroke, and CHD in overweight/obese T2D patients.
背景
据报道，绿茶可能对心血管疾病（CVD）的发生具有保护作用。本研究旨在调查超重/肥胖的2型糖尿病（T2D）患者中绿茶摄入量与CVD发病之间的关联。
方法
共招募了4756名中国超重/肥胖的T2D患者，并进行了6.27年的随访。在基线时通过访员管理的问卷收集绿茶摄入量信息。使用Cox比例风险模型估计根据绿茶摄入量得出的CVD发病风险比（HR）和95%置信区间（CI）。
结果
与非习惯性饮用者相比，每天饮用超过5克茶叶的参与者患CVD的风险降低了29%（95%CI：0.55 - 0.92），中风风险降低了30%（95%CI：0.51 - 0.95），冠心病（CHD）风险降低了40%（95%CI：0.40 - 0.89）。同样，饮用绿茶≥40年的参与者患CVD的风险降低了31%（95%CI：0.54 - 0.88），中风风险降低了33%（95%CI：0.50 - 0.90），CHD风险降低了39%（95%CI：0.42 - 0.88）。在T2D病史<5年的参与者中，每天饮用超过5克茶叶和饮用茶叶超过40年分别使中风风险降低了59%（95%CI：0.23 - 0.72）和57%（95%CI：0.26 - 0.74）。然而，在T2D病史≥5年的参与者中，每天饮用超过5克茶叶和饮用茶叶超过40年分别使CHD风险降低了50%（95%CI：0.30 - 0.82）和46%（95%CI：0.35 - 0.85）。
结论
超重/肥胖的T2D患者饮用绿茶与降低CVD、中风和CHD风险相关。
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