绿茶对2型糖尿病患者的影响：一项荟萃分析。

The effect of green tea on patients with type 2 diabetes mellitus: A meta-analysis.

作者信息

Jia Ming-Jie, Liu Xing-Ning, Liang Ying-Chao, Liu De-Liang, Li Hui-Lin

机构信息

The Fourth Clinical Medical College of Guangzhou University of Chinese Medicine, Shenzhen, Guangdong, China.

Shenzhen Traditional Chinese Medicine Hospital, Shenzhen, Guangdong, China.

出版信息

Medicine (Baltimore). 2024 Nov 22;103(47):e39702. doi: 10.1097/MD.0000000000039702.

BACKGROUND

To systematically evaluate the effect of green tea on patients with type 2 diabetes.

METHODS

A computer search Cochrane, PubMed, Embase, CNKI, Wanfang, VIP, and other Chinese and English databases were conducted for randomized controlled trials of green tea in the treatment of patients with type 2 diabetes. The duration of these trials spanned from the establishment of the database to January 10, 2024. The obtained data were subjected to meta-analysis using Stata15.1 software. A total of 15 articles were included, encompassing 722 patients.

RESULTS

The meta-analysis results showed that compared to the control group, green tea intervention significantly improved the improvement of fasting blood glucose (SMD = -0.41, 95% CI: -0.67 to -0.19, P = .001), glycated hemoglobin (SMD = -0.68, 95% CI: -1.15 to 0.21, P = .004) and insulin resistance index (SMD = -0.70, 95% CI: -1.18 to -0.22, P = .005) in the experimental group compared to the control group. The differences were statistically significant (P < .05).

CONCLUSION

Green tea significantly improves fasting blood glucose, glycated hemoglobin and insulin resistance in patients with type 2 diabetes.

背景

系统评价绿茶对2型糖尿病患者的影响。

方法

通过计算机检索Cochrane、PubMed、Embase、中国知网、万方、维普等中英文数据库，查找绿茶治疗2型糖尿病患者的随机对照试验。检索时间范围为各数据库建库至2024年1月10日。采用Stata15.1软件对获取的数据进行荟萃分析。共纳入15篇文章，涉及722例患者。

结果

荟萃分析结果显示，与对照组相比，绿茶干预显著改善了试验组患者的空腹血糖（标准化均数差[SMD]= -0.41，95%置信区间[CI]：-0.67至-0.19，P = 0.001）、糖化血红蛋白（SMD = -0.68，95% CI：-1.15至-0.21，P = 0.004）和胰岛素抵抗指数（SMD = -0.70，95% CI：-1.18至-0.22，P = 0.005）。差异具有统计学意义（P < 0.05）。