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The Problem of Diagnosing Prostate Cancer-The Promise of Ion Channels as Novel Biomarkers of Disease!

作者信息

Djamgoz Mustafa B A, Foster Christopher S

机构信息

Imperial College London, London, United Kingdom.

Independent Consultant, London, United Kingdom.

出版信息

Bioelectricity. 2025 Mar 18;7(1):76-77. doi: 10.1089/bioe.2024.0042. eCollection 2025 Mar.

DOI:10.1089/bioe.2024.0042
PMID:40342941
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12054604/
Abstract
摘要

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本文引用的文献

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J Steroid Biochem Mol Biol. 2024 Oct;243:106588. doi: 10.1016/j.jsbmb.2024.106588. Epub 2024 Jul 19.
2
Electrical excitability of cancer cells-CELEX model updated.癌细胞的电兴奋性 - CELEX 模型更新。
Cancer Metastasis Rev. 2024 Dec;43(4):1579-1591. doi: 10.1007/s10555-024-10195-6. Epub 2024 Jul 8.
3
Ranolazine: a potential anti-metastatic drug targeting voltage-gated sodium channels.雷诺嗪：一种靶向电压门控钠离子通道的潜在抗转移药物。
Br J Cancer. 2024 May;130(9):1415-1419. doi: 10.1038/s41416-024-02622-w. Epub 2024 Feb 29.
4
Prostate cancer: Novel genetic and immunologic biomarkers.前列腺癌：新型遗传和免疫生物标志物。
Clin Chim Acta. 2024 Mar 1;555:117824. doi: 10.1016/j.cca.2024.117824. Epub 2024 Feb 3.
5
Combinatorial Therapy of Cancer: Possible Advantages of Involving Modulators of Ionic Mechanisms.癌症的联合治疗：涉及离子机制调节剂的潜在优势
Cancers (Basel). 2022 May 30;14(11):2703. doi: 10.3390/cancers14112703.
6
Sodium Channel Na1.5 Controls Epithelial-to-Mesenchymal Transition and Invasiveness in Breast Cancer Cells Through its Regulation by the Salt-Inducible Kinase-1.钠离子通道 Na1.5 通过盐诱导激酶-1 的调节控制乳腺癌细胞的上皮间质转化和侵袭性。
Sci Rep. 2019 Dec 9;9(1):18652. doi: 10.1038/s41598-019-55197-5.
7
In Vivo Evidence for Voltage-Gated Sodium Channel Expression in Carcinomas and Potentiation of Metastasis.癌组织中电压门控性钠通道表达及转移增强的体内证据
Cancers (Basel). 2019 Oct 28;11(11):1675. doi: 10.3390/cancers11111675.
8
Anti-metastatic effect of ranolazine in an in vivo rat model of prostate cancer, and expression of voltage-gated sodium channel protein in human prostate.雷诺嗪对前列腺癌大鼠模型的抗转移作用，以及电压门控钠离子通道蛋白在人前列腺中的表达。
Prostate Cancer Prostatic Dis. 2019 Dec;22(4):569-579. doi: 10.1038/s41391-019-0128-3. Epub 2019 Mar 20.
9
Quantification of Total and Intracellular Sodium Concentration in Primary Prostate Cancer and Adjacent Normal Prostate Tissue With Magnetic Resonance Imaging.应用磁共振成像技术对原发性前列腺癌及毗邻正常前列腺组织中总钠和细胞内钠浓度的定量分析。
Invest Radiol. 2018 Aug;53(8):450-456. doi: 10.1097/RLI.0000000000000470.
10
Voltage-gated sodium channel activity promotes prostate cancer metastasis in vivo.电压门控钠离子通道活性促进体内前列腺癌转移。
Cancer Lett. 2012 Oct 1;323(1):58-61. doi: 10.1016/j.canlet.2012.03.036. Epub 2012 Apr 3.