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某健康区的良性胃溃疡:发病率与临床表现

Benign gastric ulceration in a health district: incidence and presentation.

作者信息

Glynn M J, Kane S P

出版信息

Postgrad Med J. 1985 Aug;61(718):695-700. doi: 10.1136/pgmj.61.718.695.

Abstract

In a survey of benign gastric ulceration conducted in the Hounslow Health District from 1981 to 1982, there was an annual incidence for this condition of 43.6 per 100,000 of the population older than 14 y, with a male:female ratio of 0.9:1. This incidence is comparable to that found in other surveys over the last 30 y, but the male:female ratio is lower than in the past. This reduction is accounted for by a rise in the peak age incidence for gastric ulcer, particularly in women, and a greater proportion of the total population in this higher age group being women. In spite of a large local Asian population, no gastric ulcers occurred in this ethnic group. Thirty-eight per cent of the patients presented with acute bleeding, and 44% of these bleeders gave a history of previous ingestion of non-steroidal anti-inflammatory drugs compared with only 14% of the non-bleeding group (P less than 0.015).

摘要

在1981年至1982年于豪恩斯洛健康区开展的一项良性胃溃疡调查中,14岁以上人群中该疾病的年发病率为每10万人43.6例,男女比例为0.9:1。这一发病率与过去30年其他调查的结果相当,但男女比例低于过去。这种下降是由于胃溃疡发病的高峰年龄上升,尤其是在女性中,且该较高年龄组中女性在总人口中所占比例更大。尽管当地有大量亚洲人口,但该族群未出现胃溃疡病例。38%的患者表现为急性出血,这些出血患者中有44%有既往服用非甾体抗炎药的病史,而非出血组这一比例仅为14%(P<0.015)。

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