Brandt Alyssa, Leslie Zachary, Rawson Mitch, Ikramuddin Sayeed, Wise Eric
Department of Surgery, University of Minnesota Medical School, MMC 195, 420 Delaware Street SE, Minneapolis, MN, 55455, USA.
Carleton College, Northfield, USA.
Surg Endosc. 2025 May 9. doi: 10.1007/s00464-025-11773-7.
Elective hiatal hernia repair (HHR) is associated with reduced morbidity compared to emergent HHR. However, few studies examine the specific factors contributing to morbidity in emergent HHR. This study uses the National Inpatient Sample (NIS) database to compare the morbidity of emergent versus non-emergent HHR and identify associated risk factors.
Data from the NIS (2016-2021) were analyzed for all patients undergoing HHR. Health factors, including demographics, comorbidities, and operative details, were compared using chi-squared and T-tests. A multivariable logistic regression model was created to identify factors associated with morbidity, defined as postoperative complications such as sepsis, pneumonia, myocardial infarction, deep venous thrombosis (DVT), pulmonary embolism (PE), and others.
A total of 723,000 records existed with a hiatal hernia diagnosis code. Of these, 67,059 patients underwent HHR, with 61,586 (91.8%) undergoing non-emergent HHR. Emergent HHR was associated with increased morbidity (OR 3.95, 95% CI 1.0-1.05, p < 0.05). Risk factors for increased morbidity in both groups included hypertension and advanced age. Protective factors included female gender, GERD, and prior bariatric surgery. Diabetes increased morbidity in emergent HHR but not non-emergent HHR. Smoking, Medicare/Medicaid, mesh use, COPD, and history of DVT increased morbidity in elective HHR, but not emergent HHR. The robotic approach increased morbidity in non-emergent HHR but decreased it in emergent HHR.
Emergent HHR is associated with higher morbidity compared to non-emergent HHR. Risk factors like smoking, COPD, and DVT increase morbidity in non-emergent HHR, while female gender, GERD, and prior bariatric surgery are protective. The NIS database provides valuable insights into the morbidity associated with HHR and can guide surgical decision-making.
与急诊食管裂孔疝修补术(HHR)相比,择期HHR的发病率较低。然而,很少有研究探讨导致急诊HHR发病的具体因素。本研究使用国家住院样本(NIS)数据库比较急诊与非急诊HHR的发病率,并确定相关危险因素。
对NIS(2016 - 2021年)中所有接受HHR的患者数据进行分析。使用卡方检验和T检验比较健康因素,包括人口统计学、合并症和手术细节。建立多变量逻辑回归模型以确定与发病率相关的因素,发病率定义为术后并发症,如败血症、肺炎、心肌梗死、深静脉血栓形成(DVT)、肺栓塞(PE)等。
共有723,000条记录存在食管裂孔疝诊断代码。其中,67,059例患者接受了HHR,61,586例(91.8%)接受了非急诊HHR。急诊HHR与发病率增加相关(OR 3.95,95% CI 1.0 - 1.05,p < 0.05)。两组发病率增加的危险因素包括高血压和高龄。保护因素包括女性、胃食管反流病(GERD)和既往减重手术。糖尿病增加了急诊HHR的发病率,但未增加非急诊HHR的发病率。吸烟、医疗保险/医疗补助、使用补片、慢性阻塞性肺疾病(COPD)和DVT病史增加了择期HHR的发病率,但未增加急诊HHR的发病率。机器人手术方法增加了非急诊HHR的发病率,但降低了急诊HHR的发病率。
与非急诊HHR相比,急诊HHR的发病率更高。吸烟、COPD和DVT等危险因素增加了非急诊HHR的发病率,而女性、GERD和既往减重手术具有保护作用。NIS数据库为与HHR相关的发病率提供了有价值的见解,并可指导手术决策。