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年龄和紧急手术需求对食管裂孔疝修补术结果的影响。

The Impact of Age and Need for Emergent Surgery in Paraesophageal Hernia Repair Outcomes.

机构信息

Department of Cardiothoracic Surgery, Stanford University, Stanford, California.

Society of Thoracic Surgeons Research Center, Chicago, Illinois.

出版信息

Ann Thorac Surg. 2023 Jul;116(1):138-145. doi: 10.1016/j.athoracsur.2023.01.017. Epub 2023 Jan 23.

DOI:10.1016/j.athoracsur.2023.01.017
PMID:36702291
Abstract

BACKGROUND

Observation of paraesophageal hernias (PEHs) may lead to emergent surgery for hernia-related complications. This study evaluated urgent or emergent repair outcomes to quantify the possible sequelae of failed conservative PEH management.

METHODS

The impact of operative status (elective vs urgent or emergent) on perioperative mortality or major morbidity for patients who underwent hiatal hernia repair for a PEH diagnosis from 2012 to 2021 in the Society of Thoracic Surgery General Thoracic Surgery Database was evaluated with multivariable logistic regression models.

RESULTS

Overall, 2082 (10.9%) of 19,122 patients with PEHs underwent urgent or emergent repair. Patients undergoing nonelective surgery were significantly older than patients undergoing elective surgery (median age, 73 years [interquartile range, 63-82 years] vs 66 years [interquartile range, 58-74 years]) and had a lower preoperative performance score (P < .001). Nonelective surgical procedures were more likely to be performed through the chest or by laparotomy rather than by laparoscopy (20% vs 11.4%; P < .001), and they were associated with longer hospitalizations (4 days vs 2 days; P < .001), higher operative mortality (4.5% vs 0.6%; P < .001), and higher major morbidity (27% vs 5.5%; P < .001). Nonelective surgery was a significant independent predictor of major morbidity in multivariable analysis (odds ratio, 2.06; P < .001). Patients more than the age of 80 years had higher operative mortality (4.3% vs 0.6%; P < 0.001) and major morbidity (19% vs 6.1%; P < .001) than younger patients overall, and these older patients more often had nonelective surgery (26% vs 8.6%; P < .001) CONCLUSIONS: The operative morbidity of PEH repair is significantly increased when surgery is nonelective, particularly for older patients. These results can inform the potential consequences of choosing watchful waiting vs elective PEH repair.

摘要

背景

观察食管裂孔疝(PEH)可能导致疝相关并发症的紧急手术。本研究评估了紧急或急症修复的结果,以量化保守性 PEH 管理失败的可能后果。

方法

在 2012 年至 2021 年期间,胸外科协会胸外科普通数据库中,对因 PEH 诊断而行食管裂孔疝修补术的患者,通过多变量逻辑回归模型评估手术状态(选择性与紧急或急症)对围手术期死亡率或主要发病率的影响。

结果

总体而言,19122 例 PEH 患者中有 2082 例(10.9%)接受了紧急或急症修复。与选择性手术相比,非选择性手术患者年龄明显较大(中位年龄,73 岁[四分位距,63-82 岁]比 66 岁[四分位距,58-74 岁]),术前表现评分较低(P <.001)。非选择性手术更有可能通过胸部或剖腹进行,而不是通过腹腔镜进行(20%比 11.4%;P <.001),并且与住院时间延长(4 天比 2 天;P <.001)、手术死亡率升高(4.5%比 0.6%;P <.001)和主要发病率升高(27%比 5.5%;P <.001)相关。在多变量分析中,非选择性手术是主要发病率的显著独立预测因素(比值比,2.06;P <.001)。80 岁以上的患者手术死亡率(4.3%比 0.6%;P < 0.001)和主要发病率(19%比 6.1%;P <.001)均高于整体年轻患者,这些老年患者更常接受非选择性手术(26%比 8.6%;P <.001)。

结论

当手术为非选择性时,PEH 修复的手术发病率显著增加,尤其是对于老年患者。这些结果可以为选择观察等待与选择性 PEH 修复的潜在后果提供信息。

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