Bhakkan-Mambir Bernard, Luce Danièle, Deloumeaux Jacqueline
Registre Général Des Cancers de Guadeloupe, Centre Hospitalier Universitaire de la Guadeloupe, Guadeloupe F. W. I. Route de Chauvel, Pointe-à-Pitre Cedex, 97159, France.
Irset (Institut de Recherche En Santé, environnement et travail)-UMR_S 1085, Inserm, Univ Rennes, Univ Antilles, EHESP, Pointe-à-Pitre, Guadeloupe, F-97100, France.
BMC Public Health. 2025 May 9;25(1):1723. doi: 10.1186/s12889-025-22896-w.
People living in the vicinity of a landfill may be exposed to a wide range of pollutants, with possible subsequent health effects, including increased risks of cancer. The aim of the present study was to explore associations between cancer incidence and proximity to the main open landfills in Guadeloupe.
We used data from the Guadeloupe cancer registry over the period from 2008 to 2017. We conducted analyses for the 18 most frequent cancer sites. We used the Besag York and Mollié model to study the association between cancer incidence and distance from a landfill, with adjustment for social deprivation.
People who lived less than 2 km from a landfill had increased risks of ovarian and head and neck cancer. Elevated risks of pancreatic cancer, prostate cancer, lung cancer and melanoma in men, as well colon cancer and hormone receptor-negative breast cancer in women, were also observed.
A link between exposure to pollutants generated by a landfill and the risk of developing certain cancers was suggested but should be confirmed by additional studies involving a better characterization of exposure and control of potential confounders.
生活在垃圾填埋场附近的人们可能会接触到多种污染物，随后可能会对健康产生影响，包括患癌风险增加。本研究的目的是探讨瓜德罗普岛主要露天垃圾填埋场附近地区与癌症发病率之间的关联。
我们使用了瓜德罗普岛癌症登记处2008年至2017年期间的数据。我们对18个最常见的癌症部位进行了分析。我们使用贝萨格·约克和莫利模型来研究癌症发病率与距离垃圾填埋场的距离之间的关联，并对社会剥夺情况进行了调整。
居住在距离垃圾填埋场不到2公里处的人群患卵巢癌、头颈癌的风险增加。还观察到男性患胰腺癌、前列腺癌、肺癌和黑色素瘤的风险升高，以及女性患结肠癌和激素受体阴性乳腺癌的风险升高。
研究表明垃圾填埋场产生的污染物暴露与患某些癌症的风险之间存在联系，但这一联系应通过进一步研究予以证实，这些研究需更好地描述暴露情况并控制潜在的混杂因素。
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