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基于含热响应聚合物共混膜的有机电化学晶体管

Organic Electrochemical Transistors Based on Blend Films with Thermoresponsive Polymer.

作者信息

Yamamoto Shunsuke, Kindaichi Shuhei, Matsubara Ryosuke, Kubono Atsushi, Giridharagopal Rajiv, Ginger David S, Mitsuishi Masaya

机构信息

Graduate School of Engineering, Tohoku University, 6-6-11 Aramaki Aza Aoba, Aoba-ku, Sendai, 980-8579, Japan.

Graduate School of Engineering, Kyoto University, Katsura, Nishikyo-ku, Kyoto, 615-8510, Japan.

出版信息

Small. 2025 Jun;21(25):e2501927. doi: 10.1002/smll.202501927. Epub 2025 May 10.

DOI:10.1002/smll.202501927
PMID:40346972
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12199101/
Abstract

Organic electrochemical transistors (OECTs) are biocompatible devices with significant potential for biosensing. Functionalizing the channel layers is essential for improving the selectivity and sensitivity of OECT-based biosensors. A straightforward one-step fabrication method for these functionalized channel layers can simplify the production process for these devices. This study developed OECT devices based on a polymer blend of poly(3,4-ethylenedioxythiophene)-poly(styrenesulfonate) (PEDOT:PSS) and poly(N-isopropylacrylamide) (PNIPAM) that respond to temperature changes. Structural analyses of the blended films showed that hole transport through PEDOT is maintained even after blending, and the PNIPAM is segregated at the surface. To overcome the large chain conformational change that occurs with temperature changes, a flexible poly(ethylene glycol) diglycidyl ether (PEGDE) crosslinker is used in addition to the conventional crosslinker, (3-glycidyloxypropyl)trimethoxysilane (GOPS). As a result, the PEGDE + GOPS binary crosslinker system exhibited reversible responses to temperature cycling. These results highlight two key considerations when designing a functional mixed-conductor film based on a polymer blend system: (1) vertical phase separation and (2) proper crosslinker selection.

摘要

有机电化学晶体管（OECTs）是具有生物传感巨大潜力的生物相容性器件。使通道层功能化对于提高基于OECT的生物传感器的选择性和灵敏度至关重要。一种用于这些功能化通道层的直接一步制造方法可以简化这些器件的生产过程。本研究开发了基于聚（3,4-乙撑二氧噻吩）-聚（苯乙烯磺酸盐）（PEDOT:PSS）和聚（N-异丙基丙烯酰胺）（PNIPAM）的聚合物共混物且对温度变化有响应的OECT器件。共混膜的结构分析表明，即使在共混后，通过PEDOT的空穴传输仍得以保持，并且PNIPAM在表面发生偏析。为了克服温度变化时发生的大的链构象变化，除了传统交联剂（3-缩水甘油氧基丙基）三甲氧基硅烷（GOPS）之外，还使用了柔性聚乙二醇二缩水甘油醚（PEGDE）交联剂。结果，PEGDE + GOPS二元交联剂体系对温度循环表现出可逆响应。这些结果突出了在基于聚合物共混体系设计功能性混合导体膜时的两个关键考虑因素：（1）垂直相分离和（2）合适的交联剂选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6774/12199101/295187f1070c/SMLL-21-2501927-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6774/12199101/197ff7569a59/SMLL-21-2501927-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6774/12199101/d834ca78b1e6/SMLL-21-2501927-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6774/12199101/0eb11d66758d/SMLL-21-2501927-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6774/12199101/8e8d1c6768f2/SMLL-21-2501927-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6774/12199101/bc45e6c222ec/SMLL-21-2501927-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6774/12199101/28fc43e30211/SMLL-21-2501927-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6774/12199101/0b4af2e336f8/SMLL-21-2501927-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6774/12199101/295187f1070c/SMLL-21-2501927-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6774/12199101/197ff7569a59/SMLL-21-2501927-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6774/12199101/d834ca78b1e6/SMLL-21-2501927-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6774/12199101/0eb11d66758d/SMLL-21-2501927-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6774/12199101/8e8d1c6768f2/SMLL-21-2501927-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6774/12199101/bc45e6c222ec/SMLL-21-2501927-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6774/12199101/28fc43e30211/SMLL-21-2501927-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6774/12199101/0b4af2e336f8/SMLL-21-2501927-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6774/12199101/295187f1070c/SMLL-21-2501927-g004.jpg

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本文引用的文献

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