[越南献血者中乙肝病毒标志物的流行情况]

[Prevalence of hepatitis B viral markers in Vietnamese blood donors].

作者信息

Hoang B, Simonneau M, Le Xuan P, Audat F, Guichoux P, Jaulmes B

出版信息

Rev Fr Transfus Immunohematol. 1985 Jun;28(3):227-36. doi: 10.1016/s0338-4535(85)80114-8.

Abstract

Serum samples were assayed using radioimmunoassay in 573 Vietnamese blood donors living in Hanoï (North Viet Nam). 66 (11.5%) subjects were HBsAg-positive. Of these 66 HBsAg carriers, 17 (25,8%) were positive for hepatitis B e antigen (HBeAg) and 43 (65.1%) for antibody to HBeAg (anti-HBe). 22 (3.8%) subjects were positive for antibody to hepatitis B core antigen (anti-HBc) alone. 402 (70.2%) subjects were positive for antibody to HBsAg (anti-HBs). This anti-HBs percentage increased with age. Only 83 (14.5%) subjects were negative for all hepatitis B viral (HBV) markers. This no HBV markers percentage decreased with age. The chi 2 test showed a non significant difference for frequencies of HBsAg, anti-HBc alone, anti-HBs but a significant one for frequencies of no HBV markers in men and women.

摘要

采用放射免疫分析法对573名居住在河内（越南北部）的越南献血者的血清样本进行检测。66名（11.5%）受试者乙肝表面抗原（HBsAg）呈阳性。在这66名HBsAg携带者中，17名（25.8%）乙肝e抗原（HBeAg）呈阳性，43名（65.1%）乙肝e抗体（抗-HBe）呈阳性。22名（3.8%）受试者仅乙肝核心抗体（抗-HBc）呈阳性。402名（70.2%）受试者乙肝表面抗体（抗-HBs）呈阳性。该抗-HBs百分比随年龄增长而升高。仅83名（14.5%）受试者所有乙肝病毒（HBV）标志物均呈阴性。该无HBV标志物百分比随年龄增长而降低。卡方检验显示，HBsAg、仅抗-HBc、抗-HBs的频率在男性和女性中无显著差异，但无HBV标志物的频率有显著差异。