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电针治疗偏头痛的随机对照试验的系统评价与Meta分析

A Systematic Review and Meta-Analysis of Randomized Controlled Trials for Electroacupuncture Treatment of Migraine.

作者信息

Song ShiWei, Chen Hao

机构信息

Department of Traditional Chinese Medicine, Sichuan Taikang Hospital, Chengdu, Sichuan, People's Republic of China.

Chengdu University of Traditional Chinese Medicine CN, Chengdu, Sichuan, People's Republic of China.

出版信息

J Pain Res. 2025 May 6;18:2321-2333. doi: 10.2147/JPR.S518294. eCollection 2025.

Abstract

PURPOSE

Numerous clinical studies have shown that patients with migraine can benefit from electroacupuncture treatment. However, there are no published systematic reviews and meta-analyses of pure electroacupuncture for migraine. Therefore, we conducted a meta-analysis to evaluate the efficacy of pure electroacupuncture as a standalone treatment for migraine patients.

PATIENTS AND METHODS

We searched Six electronic databases. All from the inception to August 1st, 2024. In the literature, clinical investigators evaluated the efficacy and safety of electroacupuncture as the primary treatment for migraine. Researchers assessed the quality of the studies using the Cochrane Handbook for Systematic Reviews of Interventions. The Review Manager 5.4 software was used to perform statistical analysis.

RESULTS

Ten randomized controlled trials involving 1161 people were included. The meta-analysis yielded a substantial result: the application of pure electroacupuncture significantly improved the effective rate compared to the control group. In the visual analogue scale score, the present study found no significant difference between electroacupuncture and Western medicine as standalone treatments. Regarding migraine-associated symptom scores, the experimental group exhibited no superiority in comparison to the control group. Moreover, following the intervention, several significant changes were observed in the secondary outcome indicators between the two groups, including cerebral arterial blood flow velocity, the migraine attack days, the lasting time of headache remission, mean time of the headache attack, duration of the headache attack, and the migraine-specific quality of life questionnaire score, with the results proving to be statistically significant.

CONCLUSION

The results of the analysis suggested that pure electroacupuncture is beneficial for migraine patients, but it remains difficult to obtain comprehensive data. Our study is supported by evidence of low to moderate quality. It is necessary to further confirm the efficacy of pure electroacupuncture for migraine with higher-quality clinical research.

摘要

目的

众多临床研究表明偏头痛患者可从电针治疗中获益。然而,尚无关于单纯电针治疗偏头痛的系统评价和荟萃分析发表。因此,我们进行了一项荟萃分析,以评估单纯电针作为偏头痛患者独立治疗方法的疗效。

患者与方法

我们检索了六个电子数据库。时间范围均从数据库建立至2024年8月1日。在文献中,临床研究人员评估了电针作为偏头痛主要治疗方法的疗效和安全性。研究人员使用《Cochrane干预措施系统评价手册》评估研究质量。使用Review Manager 5.4软件进行统计分析。

结果

纳入了10项涉及1161人的随机对照试验。荟萃分析得出了一个重要结果:与对照组相比,单纯电针的应用显著提高了有效率。在视觉模拟量表评分方面,本研究发现电针与西药作为独立治疗方法时无显著差异。关于偏头痛相关症状评分,实验组与对照组相比无优势。此外,干预后,两组间的次要结局指标出现了一些显著变化,包括脑动脉血流速度、偏头痛发作天数头痛缓解持续时间、头痛发作平均时间、头痛发作持续时间以及偏头痛特异性生活质量问卷评分,结果具有统计学意义。

结论

分析结果表明单纯电针治疗对偏头痛患者有益,但仍难以获得全面数据。我们的研究得到了低至中等质量证据的支持。有必要通过更高质量的临床研究进一步证实单纯电针对偏头痛的疗效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a4dd/12065461/2e636a9d86b2/JPR-18-2321-g0001.jpg

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