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A Case of Supratentorial Lymphocytic Inflammation with Parenchymal Perivascular Enhancement Responsive to Steroids (SLIPPERS) with Associated Chronic Lymphocytic Inflammation with Pontine Perivascular Enhancement Responsive to Steroids (CLIPPERS) and a Review of Literature.

作者信息

Mirg Shivam, Das Animesh, Parashar Akhil, Tripathi Manjari, Garg Ajay

机构信息

Department of Neurology, All India Institute of Medical Sciences, New Delhi, India.

Department of Neuro-radiology, All India Institute of Medical Sciences, New Delhi, India.

出版信息

Ann Indian Acad Neurol. 2025 May 1;28(3):474-476. doi: 10.4103/aian.aian_998_24. Epub 2025 May 5.

DOI:10.4103/aian.aian_998_24
PMID:40354514
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12192379/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e98f/12192379/73b0545385e6/AIAN-28-474-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e98f/12192379/73b0545385e6/AIAN-28-474-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e98f/12192379/73b0545385e6/AIAN-28-474-g001.jpg

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A Case of Supratentorial Lymphocytic Inflammation with Parenchymal Perivascular Enhancement Responsive to Steroids (SLIPPERS) with Associated Chronic Lymphocytic Inflammation with Pontine Perivascular Enhancement Responsive to Steroids (CLIPPERS) and a Review of Literature.1例幕上淋巴细胞性炎症伴实质血管周围强化且对类固醇有反应(SLIPPERS)合并桥脑淋巴细胞性炎症伴血管周围强化且对类固醇有反应(CLIPPERS)及文献复习
Ann Indian Acad Neurol. 2025 May 1;28(3):474-476. doi: 10.4103/aian.aian_998_24. Epub 2025 May 5.
2
Clinical characteristics, management, and outcomes of CLIPPERS: A comprehensive systematic review of 140 patients from 100 studies.伴有皮质下梗死和白质脑病的常染色体隐性遗传性脑动脉病(CLIPPERS)的临床特征、治疗及预后:对100项研究中140例患者的全面系统评价
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3
Supratentorial lymphocytic inflammation with parenchymal perivascular enhancement responsive to steroids: A case report and literature review.幕上淋巴细胞性炎症伴实质性血管周围强化且对类固醇有反应:病例报告及文献综述
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4
Supratentorial Lymphocytic Inflammation with Parenchymal Perivascular Enhancement Responsive to Steroids (SLIPPERS)-Does it Really Exist?对类固醇有反应的幕上淋巴细胞性炎症伴实质血管周围强化(SLIPPERS)——它真的存在吗?
Brain Sci. 2023 Aug 11;13(8):1191. doi: 10.3390/brainsci13081191.
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The Elusive SLIPPERS Syndrome (Supratentorial Lymphocytic Inflammation with Parenchymal Perivascular Enhancement Responsive to Steroids): A Case Report and Literature Review.难以捉摸的SLIPPERS综合征(幕上淋巴细胞性炎症伴实质血管周围强化且对类固醇有反应):病例报告及文献综述
Int Med Case Rep J. 2023 Jun 10;16:357-361. doi: 10.2147/IMCRJ.S411204. eCollection 2023.
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Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids, a mimicker of malignancy: a case report and review of the literature.类固醇反应性伴有脑桥血管周围强化的慢性淋巴细胞性炎症,酷似恶性肿瘤:病例报告及文献复习。
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Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS): A lymphocytic reactive response of the central nervous system? A case report.类固醇反应性桥脑周围血管强化的慢性淋巴细胞性炎症(CLIPPERS):一种中枢神经系统的淋巴细胞反应性病变?一例报告
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CLIPPERS: chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids. Review of an increasingly recognized entity within the spectrum of inflammatory central nervous system disorders.CLIPPERS:伴有脑桥血管周围强化的慢性淋巴细胞性炎症,对类固醇治疗有反应。对炎症性中枢神经系统疾病范围内一种日益被认识的病症的综述。
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引用本文的文献

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Probable chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids syndrome: management with corticosteroids and intravenous immunoglobulin-a case report.可能的桥脑周围血管增强性慢性淋巴细胞性炎症对类固醇有反应综合征:用皮质类固醇和静脉注射免疫球蛋白治疗——病例报告
J Med Case Rep. 2025 Jul 17;19(1):351. doi: 10.1186/s13256-025-05402-z.

本文引用的文献

1
Supratentorial Lymphocytic Inflammation with Parenchymal Perivascular Enhancement Responsive to Steroids: A Potentially Overlooked Diagnosis.幕上淋巴细胞性炎症伴实质血管周围强化且对类固醇有反应:一种可能被忽视的诊断。
Ann Neurol. 2024 Feb;95(2):407-409. doi: 10.1002/ana.26821. Epub 2023 Nov 7.
2
Supratentorial Lymphocytic Inflammation with Parenchymal Perivascular Enhancement Responsive to Steroids (SLIPPERS)-Does it Really Exist?对类固醇有反应的幕上淋巴细胞性炎症伴实质血管周围强化(SLIPPERS)——它真的存在吗?
Brain Sci. 2023 Aug 11;13(8):1191. doi: 10.3390/brainsci13081191.
3
The Elusive SLIPPERS Syndrome (Supratentorial Lymphocytic Inflammation with Parenchymal Perivascular Enhancement Responsive to Steroids): A Case Report and Literature Review.
难以捉摸的SLIPPERS综合征(幕上淋巴细胞性炎症伴实质血管周围强化且对类固醇有反应):病例报告及文献综述
Int Med Case Rep J. 2023 Jun 10;16:357-361. doi: 10.2147/IMCRJ.S411204. eCollection 2023.
4
Clinical characteristics, management, and outcomes of CLIPPERS: A comprehensive systematic review of 140 patients from 100 studies.伴有皮质下梗死和白质脑病的常染色体隐性遗传性脑动脉病(CLIPPERS)的临床特征、治疗及预后:对100项研究中140例患者的全面系统评价
Mult Scler Relat Disord. 2022 Dec;68:104112. doi: 10.1016/j.msard.2022.104112. Epub 2022 Aug 18.
5
Case 302: Supratentorial Lymphocytic Inflammation with Parenchymal Perivascular Enhancement Responsive to Steroids.病例 302:伴有实质血管周围强化的幕上淋巴细胞炎症,对类固醇有反应。
Radiology. 2022 Jun;303(3):726-730. doi: 10.1148/radiol.204423.
6
Supratentorial lymphocytic inflammation with parenchymal perivascular enhancement responsive to steroids: A case report and literature review.幕上淋巴细胞性炎症伴实质性血管周围强化且对类固醇有反应:病例报告及文献综述
Surg Neurol Int. 2021 Jul 6;12:327. doi: 10.25259/SNI_355_2021. eCollection 2021.
7
CLIPPERS and its mimics: evaluation of new criteria for the diagnosis of CLIPPERS.CLIPPERS 及其模拟物:新的 CLIPPERS 诊断标准的评估。
J Neurol Neurosurg Psychiatry. 2019 Sep;90(9):1027-1038. doi: 10.1136/jnnp-2018-318957. Epub 2019 May 9.
8
Horizontal eyeball akinesia as an initial manifestation of CLIPPERS: Case report and review of literature.水平眼球运动不能作为慢性淋巴细胞性炎症伴脑桥血管周围强化症(CLIPPERS)的首发表现:病例报告及文献复习
Medicine (Baltimore). 2016 Aug;95(34):e4640. doi: 10.1097/MD.0000000000004640.