Lozano-Sanroma Javier, Barros Alberto, Queiruga-Piñeiro Juan, Alcalde Ignacio, Alvarado-Villacorta Rosa, Fernández-Vega Cueto-Felgueroso Luis, Merayo-Lloves Jesús
Optometry Department, University Institute Fernández-Vega, Ophthalmological Research Foundation, Oviedo, Spain.
Ocular Surface and Nerve Regeneration Research, University Institute Fernández-Vega, Ophthalmological Research Foundation, Oviedo, Spain.
Medicine (Baltimore). 2025 May 9;104(19):e42383. doi: 10.1097/MD.0000000000042383.
BACKGROUND: Corneal esthesiometry plays a key role in assessing the integrity of the ocular surface. Its importance lies in the fact that several eye and systemic conditions can alter the corneal sensitivity. This is evidenced by the emergence of new devices to measure this parameter in recent years. METHODS: Publications found in Web of Science and Scopus databases from 2000 to 2024 were analyzed. Microsoft Excel, Rayyan, and VOSviewer software were used. RESULTS: A total of 556 articles were included in the study. Andrew JM Boulton had the greatest impact, with the highest h-index. The Centre for Contact Lens Research, School of Optometry, University of Waterloo (Canada), was the most prolific institution, with 25 articles published. The United States led the ranking of countries, with 81 publications. Six keyword clusters were identified, encompassing neurophysiology, dry eye, ocular pathology, diabetic neuropathy, structural nerve assessment, and refractive surgery. CONCLUSION: This study reports on who, why, how many, and where corneal esthesiometry has been studied, through a bibliometric analysis. The studies centered on sensory physiology, ocular surface disease, and dry eye disease. These emerging trends highlight new clinical, diagnostic, and research perspectives, which may guide future investigations and contribute to more precise strategies for the treatment of ocular surface conditions.
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