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用于生物技术应用的碳基微纳机电系统综述

Review on Carbon-Based Micro and Nano Electro-Mechanical Systems for Biotechnological Application.

作者信息

Mahalakshmi M, Diana D C, Ramachandran R, Ravva Santosh Kumar, Illuri Babu, Johannah J Jeba, Manikandan T, Anand A Jose

机构信息

Department of Networking and Communications, College of Engineering and Technology, SRM Institute of Science and Technology, Kattankulathur, Chennai, 603203, India.

Department of ECE, Easwari Engineering College, Ramapuram, Chennai, 600089, India.

出版信息

Recent Pat Nanotechnol. 2025;19(4):468-482. doi: 10.2174/0118722105293232240826135124.

DOI:10.2174/0118722105293232240826135124
PMID:40356384
Abstract

The combination of carbon-based nanoelectromechanical systems (C-NEMS) and carbonbased microelectromechanical systems (C-MEMS) has become a promising new direction in biotechnology with a wide range of applications that could significantly improve medical research and healthcare. These carbon-based materials, which are highly suited for a variety of biotech applications, include graphene and carbon nanotubes (CNTs). They have special qualities including large surface area, superior electrical conductivity, and biocompatibility. The domain of medication delivery systems is where C-MEMS and C-NEMS are most prominently used. These materials address important issues with therapeutic effectiveness and patient comfort by providing a platform for targeted and regulated medication administration. Biosensors that use graphene and carbon nanotubes (CNTs) have become essential diagnostic instruments because they allow for the sensitive and realtime detection of analytes for biomarker monitoring and disease diagnosis. The incorporation of carbon- based materials into lab-on-a-chip (LOC) devices has transformed biotech tests by providing portable and quick analysis. Neural interfaces, drug screening, wearable health monitoring, diagnostics, imaging, tissue engineering and regenerative medicine, diagnostic imaging, diagnostic imaging, and imaging have all benefited greatly from the use of carbon-based materials. These wide-ranging applications of C-MEMS and C-NEMS highlight their potential to propel developments in science, medicine, healthcare and patents.

摘要

碳基纳米机电系统(C-NEMS)和碳基微机电系统(C-MEMS)的结合已成为生物技术领域一个充满前景的新方向,具有广泛的应用,可显著改善医学研究和医疗保健。这些非常适合各种生物技术应用的碳基材料包括石墨烯和碳纳米管(CNT)。它们具有诸如大表面积、卓越的导电性和生物相容性等特殊性质。C-MEMS和C-NEMS最显著的应用领域是药物输送系统。这些材料通过提供一个用于靶向和可控药物给药的平台,解决了治疗效果和患者舒适度方面的重要问题。使用石墨烯和碳纳米管(CNT)的生物传感器已成为必不可少的诊断工具,因为它们能够对分析物进行灵敏且实时的检测,用于生物标志物监测和疾病诊断。将碳基材料整合到芯片实验室(LOC)设备中,通过提供便携式和快速分析,改变了生物技术测试。神经接口、药物筛选、可穿戴健康监测、诊断、成像、组织工程和再生医学、诊断成像以及成像等领域都从碳基材料的使用中受益匪浅。C-MEMS和C-NEMS的这些广泛应用凸显了它们推动科学、医学、医疗保健和专利领域发展的潜力。

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