Heim Ursula
Institut für Ethik, Geschichte und Theorie der Medizin, Universität Münster, Von-Esmarch-Straße 62, 48149, Münster, Deutschland.
NTM. 2025 Jun;33(2):145-173. doi: 10.1007/s00048-025-00415-7. Epub 2025 May 13.
Radioisotopes were one of the defining innovations in clinical internal medicine in the post-war period. Medical university clinics used radioisotopes in the treatment of previously untreatable diseases and at the same time used them to study physiological processes in the laboratory. In the mid-1950s, new technical methods-such as scintigraphy-expanded the diagnostic and therapeutic repertoire of internal medicine. The article uses the example of isotope research to highlight the significance of technology-driven processes of change for the internal medicine clinic in West Germany. In addition, transfer processes between basic medical research and clinical research are examined and analyzed as a form of translational medicine avant la lettre.
放射性同位素是战后临床内科领域具有决定性意义的创新之一。医科大学诊所使用放射性同位素治疗此前无法治愈的疾病,同时也利用它们在实验室研究生理过程。20世纪50年代中期,闪烁扫描等新技术方法扩展了内科的诊断和治疗手段。本文以同位素研究为例,突出技术驱动的变革过程对西德内科诊所的重要性。此外,还将基础医学研究与临床研究之间的转化过程作为一种早期形式的转化医学进行审视和分析。