面向非实验室人员的高级分子检测路线图。
An Advanced Molecular Detection Roadmap for Nonlaboratorians.
作者信息
Ricaldi Jessica N, Parker J Todd, Barnes Nathelia, Turner Hannah, Santibañez Scott
出版信息
Emerg Infect Dis. 2025 May;31(13):3-8. doi: 10.3201/eid3113.241506.
Abstract
This article, aimed at nonlaboratorians such as healthcare providers, public health professionals, and policymakers, provides basic concepts and terminology to enable better understanding of other manuscripts in this advanced molecular detection journal supplement. This article focuses on 3 aspects of advanced molecular detection: pathogen genomics, bioinformatics, and public health application, while providing additional resources for understanding.
摘要
本文面向医疗服务提供者、公共卫生专业人员和政策制定者等非实验室工作人员，提供基本概念和术语，以便更好地理解这本高级分子检测期刊增刊中的其他稿件。本文重点介绍高级分子检测的三个方面：病原体基因组学、生物信息学和公共卫生应用，同时提供额外的资源以供理解。
相似文献
1
An Advanced Molecular Detection Roadmap for Nonlaboratorians.面向非实验室人员的高级分子检测路线图。
Emerg Infect Dis. 2025 May;31(13):3-8. doi: 10.3201/eid3113.241506.
2
Perceived utility and feasibility of pathogen genomics for public health practice: a survey among public health professionals working in the field of infectious diseases, Belgium, 2019.公众健康从业者对基于病原体基因组学的公共卫生实践的感知效用和可行性：比利时传染病领域公共卫生专业人员的调查，2019 年。
BMC Public Health. 2020 Aug 31;20(1):1318. doi: 10.1186/s12889-020-09428-4.
3
The Future of Whole-Genome Sequencing for Public Health and the Clinic.全基因组测序在公共卫生与临床领域的未来
J Clin Microbiol. 2016 Aug;54(8):1946-8. doi: 10.1128/JCM.01082-16. Epub 2016 Jun 15.
4
Next Generation Sequencing and Bioinformatics Methodologies for Infectious Disease Research and Public Health: Approaches, Applications, and Considerations for Development of Laboratory Capacity.下一代测序和生物信息学方法在传染病研究和公共卫生中的应用：建立实验室能力的方法、应用和考虑因素。
J Infect Dis. 2020 Mar 28;221(Suppl 3):S292-S307. doi: 10.1093/infdis/jiz286.
5
Promoting synergistic research and education in genomics and bioinformatics.促进基因组学和生物信息学领域的协同研究与教育。
BMC Genomics. 2008;9 Suppl 1(Suppl 1):I1. doi: 10.1186/1471-2164-9-S1-I1.
6
Development of rationally designed nucleic acid signatures for microbial pathogens.用于微生物病原体的合理设计核酸特征的开发。
Expert Rev Mol Diagn. 2004 May;4(3):303-15. doi: 10.1586/14737159.4.3.303.
7
Molecular diagnostics in infectious diseases and public health microbiology: cottage industry to postgenomics.传染病和公共卫生微生物学中的分子诊断：从家庭作坊式产业到后基因组学时代。
Trends Mol Med. 2002 Jun;8(6):280-7. doi: 10.1016/s1471-4914(02)02349-3.
8
2005 International Conference on Metabolic Profiling. November 14-15, 2006, NC, USA.2005年国际代谢谱分析会议。2006年11月14日至15日，美国北卡罗来纳州。
Expert Rev Mol Diagn. 2006 Mar;6(2):135-6. doi: 10.1586/14737159.6.2.135.
9
10
Integrating Advanced Molecular Technologies into Public Health.将先进分子技术融入公共卫生领域。
J Clin Microbiol. 2017 Mar;55(3):703-714. doi: 10.1128/JCM.01967-16. Epub 2016 Dec 28.
本文引用的文献
1
Effects of Decentralized Sequencing on National Listeria monocytogenes Genomic Surveillance, Australia, 2016-2023.2016 - 2023年澳大利亚分散式测序对国家单核细胞增生李斯特菌基因组监测的影响
Emerg Infect Dis. 2025 May;31(13):89-97. doi: 10.3201/eid3113.241357.
2
Genomic Modeling of an Outbreak of Multidrug-Resistant Shigella sonnei, California, USA, 2023-2024.美国加利福尼亚州2023 - 2024年多重耐药性宋内志贺菌暴发的基因组建模
Emerg Infect Dis. 2025 May;31(13):98-102. doi: 10.3201/eid3113.241307.
3
Leveraging a Strategic Public-Private Partnership to Launch an Airport-Based Pathogen Monitoring Program to Detect Emerging Health Threats.利用公私战略伙伴关系启动一项基于机场的病原体监测计划，以检测新出现的健康威胁。
Emerg Infect Dis. 2025 May;31(13):35-38. doi: 10.3201/eid3113.241407.
4
Integrating Genomic Data into Public Health Surveillance for Multidrug-Resistant Organisms, Washington, USA.将基因组数据整合到耐多药生物的公共卫生监测中，美国华盛顿
Emerg Infect Dis. 2025 May;31(13):25-34. doi: 10.3201/eid3113.241227.
5
Pathogen-Agnostic Advanced Molecular Diagnostic Testing for Difficult-to-Diagnose Clinical Syndromes-Results of an Emerging Infections Network Survey of Frontline US Infectious Disease Clinicians, May 2023.针对难以诊断的临床综合征的病原体无关高级分子诊断检测——2023年5月美国一线传染病临床医生新兴感染网络调查结果
Open Forum Infect Dis. 2024 Jul 13;11(8):ofae395. doi: 10.1093/ofid/ofae395. eCollection 2024 Aug.
6
A comparison of five Illumina, Ion Torrent, and nanopore sequencing technology-based approaches for whole genome sequencing of SARS-CoV-2.比较基于 Illumina、Ion Torrent 和 nanopore 测序技术的五种方法对 SARS-CoV-2 进行全基因组测序。
Eur J Clin Microbiol Infect Dis. 2023 Jun;42(6):701-713. doi: 10.1007/s10096-023-04590-0. Epub 2023 Apr 5.
7
Rapid Diagnostic Testing for Response to the Monkeypox Outbreak - Laboratory Response Network, United States, May 17-June 30, 2022.2022 年 5 月 17 日至 6 月 30 日，美国猴痘疫情快速诊断检测反应-实验室反应网络。
MMWR Morb Mortal Wkly Rep. 2022 Jul 15;71(28):904-907. doi: 10.15585/mmwr.mm7128e1.
8
Early Detection of Severe Acute Respiratory Syndrome Coronavirus 2 Variants Using Traveler-based Genomic Surveillance at 4 US Airports, September 2021-January 2022.利用 4 个美国机场的旅行者基因组监测技术早期检测严重急性呼吸综合征冠状病毒 2 变异株，2021 年 9 月-2022 年 1 月。
Clin Infect Dis. 2023 Feb 8;76(3):e540-e543. doi: 10.1093/cid/ciac461.
9
Standardized Comparison of Different DNA Sequencing Platforms.不同DNA测序平台的标准化比较
Clin Chem. 2022 Jul 3;68(7):872-876. doi: 10.1093/clinchem/hvac023.
10
HIV Cluster and Outbreak Detection and Response: The Science and Experience.HIV聚集性和疫情检测与应对：科学与经验
Am J Prev Med. 2021 Nov;61(5 Suppl 1):S130-S142. doi: 10.1016/j.amepre.2021.05.029.
Zotero 插件