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将先进分子技术融入公共卫生领域。

Integrating Advanced Molecular Technologies into Public Health.

作者信息

Gwinn Marta, MacCannell Duncan R, Khabbaz Rima F

机构信息

CFOL, Atlanta, Georgia, USA.

Office of Infectious Diseases, Centers for Disease Control and Prevention, U.S. Department of Health and Human Services, Atlanta, Georgia, USA.

出版信息

J Clin Microbiol. 2017 Mar;55(3):703-714. doi: 10.1128/JCM.01967-16. Epub 2016 Dec 28.

Abstract

Advances in laboratory and information technologies are transforming public health microbiology. High-throughput genome sequencing and bioinformatics are enhancing our ability to investigate and control outbreaks, detect emerging infectious diseases, develop vaccines, and combat antimicrobial resistance, all with increased accuracy, timeliness, and efficiency. The Advanced Molecular Detection (AMD) initiative has allowed the Centers for Disease Control and Prevention (CDC) to provide leadership and coordination in integrating new technologies into routine practice throughout the U.S. public health laboratory system. Collaboration and partnerships are the key to navigating this transition and to leveraging the next generation of methods and tools most effectively for public health.

摘要

实验室和信息技术的进步正在改变公共卫生微生物学。高通量基因组测序和生物信息学正在提高我们调查和控制疫情、检测新发传染病、研发疫苗以及对抗抗菌药物耐药性的能力,所有这些都提高了准确性、及时性和效率。先进分子检测(AMD)计划使疾病控制与预防中心(CDC)能够在美国公共卫生实验室系统中发挥领导作用并进行协调,将新技术融入日常实践。合作与伙伴关系是驾驭这一转变并最有效地利用下一代方法和工具促进公共卫生的关键。

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