Periyasamy Sudhakar, Kaliyaperumal Prabu, Thirumalaisamy Manikandan, Balusamy Balamurugan, Elumalai Thenmozhi, Meena Veerpratap, Jadoun Vinay Kumar
School of Computer Science and Engineering, Galgotias University, 203201, Delhi NCR, India.
Department of CSBS, Rajalakshmi Engineering College, 602105, Chennai, India.
Sci Rep. 2025 May 13;15(1):16527. doi: 10.1038/s41598-025-00252-7.
The rapid spread of SARS-CoV-2 has highlighted the need for intelligent methodologies in COVID-19 diagnosis. Clinicians face significant challenges due to the virus's fast transmission rate and the lack of reliable diagnostic tools. Although artificial intelligence (AI) has improved image processing, conventional approaches still rely on centralized data storage and training. This reliance increases complexity and raises privacy concerns, which hinder global data exchange. Therefore, it is essential to develop collaborative models that balance accuracy with privacy protection. This research presents a novel framework that combines blockchain technology with a combined learning paradigm to ensure secure data distribution and reduced complexity. The proposed Combined Learning Collective Deep Learning Blockchain Model (CLCD-Block) aggregates data from multiple institutions and leverages a hybrid capsule learning network for accurate predictions. Extensive testing with lung CT images demonstrates that the model outperforms existing models, achieving an accuracy exceeding 97%. Specifically, on four benchmark datasets, CLCD-Block achieved up to 98.79% Precision, 98.84% Recall, 98.79% Specificity, 98.81% F1-Score, and 98.71% Accuracy, showcasing its superior diagnostic capability. Designed for COVID-19 diagnosis, the CLCD-Block framework is adaptable to other applications, integrating AI, decentralized training, privacy protection, and secure blockchain collaboration. It addresses challenges in diagnosing chronic diseases, facilitates cross-institutional research and monitors infectious outbreaks. Future work will focus on enhancing scalability, optimizing real-time performance and adapting the model for broader healthcare datasets.
严重急性呼吸综合征冠状病毒2(SARS-CoV-2)的迅速传播凸显了在2019冠状病毒病(COVID-19)诊断中采用智能方法的必要性。由于该病毒的快速传播速度以及缺乏可靠的诊断工具,临床医生面临着重大挑战。尽管人工智能(AI)改善了图像处理,但传统方法仍依赖集中式数据存储和训练。这种依赖增加了复杂性并引发了隐私问题,阻碍了全球数据交换。因此,开发在准确性与隐私保护之间取得平衡的协作模型至关重要。本研究提出了一种新颖的框架,该框架将区块链技术与组合学习范式相结合,以确保安全的数据分发并降低复杂性。所提出的组合学习集体深度学习区块链模型(CLCD-Block)聚合来自多个机构的数据,并利用混合胶囊学习网络进行准确预测。对肺部CT图像的广泛测试表明,该模型优于现有模型,准确率超过97%。具体而言,在四个基准数据集上,CLCD-Block的精确率高达98.79%、召回率为98.84%、特异性为98.79%、F1分数为98.81%、准确率为98.71%,展示了其卓越的诊断能力。CLCD-Block框架专为COVID-19诊断而设计,可适应其他应用,集成了人工智能、去中心化训练、隐私保护和安全的区块链协作。它解决了慢性病诊断中的挑战,促进了跨机构研究并监测传染病爆发。未来的工作将集中在提高可扩展性、优化实时性能以及使模型适用于更广泛的医疗数据集。