Stephan Brigitte, Sorbe Christina, Zyriax Birgit-Christiane, Schmittinger Janne, Augustin Matthias, Sommer Rachel, da Silva Burger Neuza Maria Bernardino, Weyergraf Ansgar, von Kiedrowski Ralph, Kühl Laura
Institute for Health Services Research in Dermatology and Nursing (IVDP), University Medical Center Hamburg-Eppendorf (UKE), 20251 Hamburg, Germany.
Midwifery Science-Health Services Research and Prevention, Institute for Health Services Research in Dermatology and Nursing (IVDP), University Medical Center Hamburg-Eppendorf (UKE), 20251 Hamburg, Germany.
Healthcare (Basel). 2025 Apr 28;13(9):1017. doi: 10.3390/healthcare13091017.
During the systemic treatment of moderate to severe psoriasis in patients of reproductive age, contraindications and therapeutic peculiarities must be taken into account. Doctor-patient communication is crucial for therapy conduct and compliance. This survey among male and female patients from the German psoriasis registry, PsoBest, aims to provide real-world evidence on communication and patient needs for those of reproductive age (18-55). In total, 404 patients were eligible for the analysis (254 m, 150 f), including 39 patients currently wishing to conceive (20 m, 19 f). Patients with and without the desire to have children received similar systemic therapy. In most cases, treatment was not adapted when patients expressed a desire to have children (85.9% m, 79.5% f). Only 38.3% of men and 49.9% of women had been informed about options for conception during or before systemic therapy, mainly by dermatologists (77.4% m, 84.6% f). The majority of patients retrieved additional information about the wish to conceive and medications from the internet and other media. This survey emphasizes the importance of open communication between patients and physicians regarding family planning and therapy options. Physicians need to broach the topic of family planning, conception and pregnancy with patients and support with evidence-based information to enable comprehensive medical decision making and safe therapy choices.
在对育龄期中度至重度银屑病患者进行系统治疗时，必须考虑禁忌证和治疗特点。医患沟通对于治疗的实施和依从性至关重要。这项针对德国银屑病登记处PsoBest的男性和女性患者的调查旨在为育龄期（18 - 55岁）患者的沟通情况和患者需求提供真实世界的证据。共有404名患者符合分析条件（男性254名，女性150名），其中包括39名目前希望怀孕的患者（男性20名，女性19名）。有生育意愿和无生育意愿的患者接受了相似的系统治疗。在大多数情况下，当患者表达生育意愿时，治疗方案并未调整（男性为85.9%，女性为79.5%）。只有38.3%的男性和49.9%的女性在系统治疗期间或之前被告知受孕选择，主要是由皮肤科医生告知的（男性为77.4%，女性为84.6%）。大多数患者从互联网和其他媒体获取了关于受孕意愿和药物的额外信息。这项调查强调了患者与医生之间就计划生育和治疗选择进行开放沟通的重要性。医生需要与患者探讨计划生育、受孕和怀孕的话题，并提供循证信息以支持患者做出全面的医疗决策和安全的治疗选择。
