Hardy Brian T, Gentile-Solomon Jessica, Solomon Jeffrey A
J Am Vet Med Assoc. 2016 Oct 15;249(8):926-930. doi: 10.2460/javma.249.8.926.
CASE DESCRIPTION A 6-year-old spayed female Golden Retriever was evaluated for a 2-week history of progressive hyporexia, signs of abdominal pain, and weight loss. CLINICAL FINDINGS Physical examination findings included mild signs of pain on palpation of the cranial part of the abdomen and a body condition score of 4 (scale, 1 to 9). A CBC revealed mild microcytosis and hypochromasia; results of serum biochemical analysis were within the respective reference ranges, and abdominal ultrasonography revealed no abnormalities. Capsule endoscopy was performed, and numerous gastric erosions and hemorrhages were detected, with rare dilated lacteals in the proximal aspect of the small intestine. TREATMENT AND OUTCOME Treatment was initiated with omeprazole and sucralfate for 6 weeks, and the dog was transitioned to a novel protein diet. Capsule endoscopy was repeated at the end of the initial treatment course and revealed overall improvement, with a few small erosions remaining; medical treatment was continued for an additional 2 weeks. At last follow-up 9 months after treatment ended, the dog was clinically normal. CLINICAL RELEVANCE Capsule endoscopy was useful for initial detection and subsequent reevaluation of gastrointestinal lesions in this patient without a need for sedation or anesthesia. Information obtained in the follow-up evaluation was valuable in identifying a need to extend the duration of medical treatment.
一只6岁已绝育的雌性金毛猎犬因持续2周的进行性食欲减退、腹痛症状和体重减轻前来接受评估。
体格检查发现,触诊腹部前部时有轻度疼痛体征,身体状况评分为4分(评分范围为1至9分)。血常规显示轻度小红细胞症和低色素血症;血清生化分析结果在各自参考范围内,腹部超声检查未发现异常。进行了胶囊内镜检查,发现大量胃糜烂和出血,在小肠近端有罕见的扩张淋巴管。
开始用奥美拉唑和硫糖铝治疗6周,然后将这只狗转换为新型蛋白质饮食。在初始治疗疗程结束时重复进行胶囊内镜检查,结果显示总体情况有所改善,仅残留一些小的糜烂;药物治疗又持续了2周。在治疗结束9个月后的最后一次随访中,这只狗临床症状正常。
胶囊内镜有助于在无需镇静或麻醉的情况下对该患者的胃肠道病变进行初步检测和后续重新评估。随访评估中获得的信息对于确定是否需要延长药物治疗时间很有价值。