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玩具贵宾犬尾状窝神经胶质瘤手术切除的经终板入路

Telovelar Approach for the Surgical Resection of a Caudal Fossa Glioma in a Toy Poodle.

作者信息

Kymm Victoria, Jeon Youngjin, Hong Il-Hwa, Roh Yoonho

机构信息

Institute of Animal Medicine, Department of Surgery, College of Veterinary Medicine, Gyeongsang National University (GNU), Jinju 52828, Republic of Korea.

Department of Veterinary Surgery, College of Veterinary Medicine, Chungnam National University, Daejeon 34134, Republic of Korea.

出版信息

Animals (Basel). 2025 Apr 28;15(9):1240. doi: 10.3390/ani15091240.

Abstract

A 7-year-old, 6.5 kg, neutered male toy poodle presented with tetraparesis, characterized by lower motor neuron signs in the forelimbs and upper motor neuron signs in the hindlimbs, along with seizures. Diagnostic imaging using magnetic resonance imaging (MRI) and computed tomography (CT) revealed a 1.4 cm × 1.4 cm × 2.2 cm mass in the fourth ventricle and caudal part of the brainstem. The surgical objective was to precisely remove masses compressing the cerebellum and brainstem. Using the telovelar approach, the tumor was partially excised, contrary to the goal of complete removal. Histopathological analysis confirmed the diagnosis of glioma. By the third postoperative day, the patient began to walk independently, and tetra-ataxia symptoms gradually decreased. Postoperative imaging confirmed the successful debulking of the tumor. By postoperative day 15, the patient showed normal gait, and adjuvant radiation therapy (RT) was initiated 2 weeks later. Unfortunately, the patient died 91 days after surgery, though the precise cause of death remains undetermined.

摘要

一只7岁、体重6.5千克的绝育雄性玩具贵宾犬出现四肢轻瘫,其特征为前肢表现为下运动神经元体征,后肢表现为上运动神经元体征,同时伴有癫痫发作。使用磁共振成像(MRI)和计算机断层扫描(CT)进行的诊断性成像显示,在第四脑室和脑干尾部有一个1.4厘米×1.4厘米×2.2厘米的肿块。手术目标是精确切除压迫小脑和脑干的肿块。采用经小脑幕入路,与完全切除的目标相反,肿瘤被部分切除。组织病理学分析确诊为神经胶质瘤。术后第三天,患者开始独立行走,四肢共济失调症状逐渐减轻。术后成像证实肿瘤成功减瘤。术后第15天,患者步态正常,两周后开始辅助放射治疗(RT)。不幸的是,患者在术后91天死亡,尽管确切死因仍未确定。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/78f0/12071118/153e0f50a1c5/animals-15-01240-g001.jpg

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