Rosendo-Chalma Pedro, Díaz-Landy Erick Nicolás, Antonio-Véjar Verónica, Ortiz Tejedor Jonnathan Gerardo, Reytor-González Claudia, Simancas-Racines Daniel, Bigoni-Ordóñez Gabriele Davide
Laboratorio de Virus y Cáncer, Unidad de Investigación Biomédica en Cáncer of Instituto de Investigaciones Biomédicas-Universidad Nacional Autónoma de México (IIB-UNAM), Mexico City 14080, Mexico.
Unidad Académica de Salud y Bienestar, Carrera de Bioquímica y Farmacia, Universidad Católica de Cuenca, Cuenca 010101, Ecuador.
Int J Mol Sci. 2025 Apr 23;26(9):3979. doi: 10.3390/ijms26093979.
Endometriosis is a chronic disease affecting approximately 10% (190 million) of women and girls of reproductive age worldwide. It is associated with a variety of often debilitating symptoms, including severe pelvic pain, pain during intercourse, bowel movements and/or urination, bloating, nausea, fatigue, risk of infertility, as well as depression and anxiety in some cases. This review summarized the pathogenesis of endometriosis and the criteria for clinical diagnosis, proposed a panel of potential biomarkers for predictive molecular diagnosis, as well as choice of treatments for pain and infertility management.
子宫内膜异位症是一种慢性疾病，全球约10%（1.9亿）的育龄妇女和女孩受其影响。它与各种常常使人衰弱的症状相关，包括严重的盆腔疼痛、性交疼痛、排便和/或排尿时疼痛、腹胀、恶心、疲劳、不孕风险，在某些情况下还包括抑郁和焦虑。本综述总结了子宫内膜异位症的发病机制和临床诊断标准，提出了一组用于预测分子诊断的潜在生物标志物，以及疼痛和不孕管理的治疗选择。
