老年人中代谢功能障碍相关脂肪性肝病、超加工食品与地中海饮食模式之间的关联
Associations Between MASLD, Ultra-Processed Food and a Mediterranean Dietary Pattern in Older Adults.
作者信息
Commins Isabella, Clayton-Chubb Daniel, Fitzpatrick Jessica A, George Elena S, Schneider Hans G, Phyo Aung Zaw Zaw, Majeed Ammar, Janko Natasha, Vaughan Nicole, Woods Robyn L, Owen Alice J, McNeil John J, Kemp William W, Roberts Stuart K
机构信息
Department of Gastroenterology, Alfred Health, Melbourne, VIC 3004, Australia.
School of Translational Medicine, Monash University, Melbourne, VIC 3004, Australia.
出版信息
Nutrients. 2025 Apr 23;17(9):1415. doi: 10.3390/nu17091415.
Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) is the most common liver disease worldwide, affecting 38% of the adult population globally. We examined the impact of the Mediterranean Diet and Ultra Processed Food (UPF) intake on the risk of prevalent MASLD in older adults. Our major findings include that increased adherence to a Mediterranean Dietary pattern was associated with a decreased risk of MASLD. Additionally, we found that high UPF intake was associated with an increased risk of MASLD. Furthermore, our study found that even with a high UPF intake, the risk of MASLD decreased if the individual also had a higher Mediterranean Diet intake compared to a lower Mediterranean Diet intake. These results are of particular importance in older people, given the known links between MASLD, metabolic comorbidities and frailty. Public health messaging should focus on promoting Mediterranean dietary habits, and ways to help older people achieve this given the social and economic barriers they may face.
代谢功能障碍相关脂肪性肝病(MASLD)是全球最常见的肝脏疾病,影响着全球38%的成年人口。我们研究了地中海饮食和超加工食品(UPF)摄入量对老年人患MASLD风险的影响。我们的主要发现包括,增加对地中海饮食模式的依从性与降低MASLD风险相关。此外,我们发现高UPF摄入量与MASLD风险增加相关。此外,我们的研究发现,即使UPF摄入量高,如果个体的地中海饮食摄入量高于较低的地中海饮食摄入量,MASLD风险也会降低。鉴于MASLD、代谢合并症和虚弱之间的已知联系,这些结果对老年人尤为重要。公共卫生宣传应侧重于促进地中海饮食习惯,以及鉴于老年人可能面临的社会和经济障碍,帮助他们实现这一目标的方法。