老年人脂肪性肝病：临床意义与未满足的需求
Steatotic Liver Disease in Older Adults: Clinical Implications and Unmet Needs.
作者信息
Clayton-Chubb Daniel, Kemp William W, Majeed Ammar, Lange Peter W, Fitzpatrick Jessica A, Vaz Karl, Lubel John S, Hodge Alexander D, Ryan Joanne, McNeil John J, Owen Alice J, Woods Robyn L, Roberts Stuart K
机构信息
Department of Gastroenterology, Alfred Health, Melbourne 3004, Australia.
School of Translational Medicine, Monash University, Melbourne 3004, Australia.
出版信息
Nutrients. 2025 Jun 30;17(13):2189. doi: 10.3390/nu17132189.
Metabolic dysfunction-associated steatotic liver disease (MASLD) is the commonest cause of chronic liver disease worldwide. Its incidence has been increasing rapidly, alongside the growing epidemics of type 2 diabetes mellitus and overweight/obesity. Global population age has also been increasing in parallel, and predictions indicate there will be more than 2 billion persons aged over 65 by the year 2050. The interplay between MASLD and other health conditions of older persons has been a focus of recent research. In this narrative review, we aim to describe its prevalence; clinical and sociodemographic associations; and outcomes for older persons, all of which are of significant importance when considering public health messaging as well as screening and counselling individual older adults.
代谢功能障碍相关脂肪性肝病（MASLD）是全球慢性肝病最常见的病因。其发病率一直在迅速上升，与此同时，2型糖尿病和超重/肥胖症的流行也在增加。全球人口年龄也在同步增长，预测表明到2050年65岁以上的人口将超过20亿。MASLD与老年人其他健康状况之间的相互作用一直是最近研究的重点。在这篇叙述性综述中，我们旨在描述其患病率、临床和社会人口学关联以及老年人的预后，所有这些在考虑公共卫生信息以及对个体老年人进行筛查和咨询时都具有重要意义。
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