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评估针对父母的特定牛奶相关症状评分Pre-CoMiSS™的必要性:一项定性研究。

Evaluating the Need for Pre-CoMiSS™, a Parent-Specific Cow's Milk-Related Symptom Score: A Qualitative Study.

作者信息

Vandenplas Yvan, Bajerová Kateřina, Dupont Christophe, Kuitunen Mikael, Meyer Rosan, Nowak-Wegrzyn Anna, Ribes-Koninckx Carmen, Salvatore Silvia, Shamir Raanan, Staiano Annamaria, Szajewska Hania, Venter Carina, Jones Sue, Järvi Anette, Couchepin Catherine

机构信息

KidZ Health Castle, UZ Brussel, Vrije Universiteit Brussel, 1090 Brussels, Belgium.

Department of Pediatrics, University Hospital Brno, Faculty of Medicine, Masaryk University, 62500 Brno, Czech Republic.

出版信息

Nutrients. 2025 Apr 30;17(9):1563. doi: 10.3390/nu17091563.

DOI:10.3390/nu17091563
PMID:40362872
原文链接:
https://pmc.ncbi.nlm.nih.gov/articles/PMC12073529/
Abstract

: Cow's milk allergy (CMA) presents a significant clinical burden. The Cow's Milk-related Symptom Score (CoMiSS™) is a widely used clinical screening tool designed to raise awareness of CMA among healthcare professionals. This qualitative study aimed to assess the need for a parent-reported CoMiSS™ tool (Pre-CoMiSS™) and explore its potential usefulness for parents and primary care physicians (PCPs). : Participants were parents of infants aged 2-12 months and PCPs from Germany, Sweden, Spain, and the United Kingdom (UK) selected from a local panel of potential respondents. Interviews, conducted by experienced qualitative research moderators, consisted of pre-decided standardised questions. Thematic analysis was undertaken, and themes were derived from the data. : A total of 26 parent interviews and 18 primary care physician interviews were conducted. Parents from all countries found the Pre-CoMiSS™ tool helpful for understanding their baby's signs, easy to use, and useful for facilitating consultation with the physician. Physicians in the UK, Spain, and Sweden found that the Pre-CoMiSS™ tool was helpful for improving symptom reporting and for medical consultations; however, in Germany, physicians had mixed opinions, expressing concerns that the tool might increase parental anxiety, lead to overdiagnosis of CMA, and add to their workload. : A parent-specific tool for recording cow's milk-related symptoms was generally well received by parents and most physicians, though concerns about parental anxiety and workload were noted, particularly in Germany. With further validation and refinement, Pre-CoMiSS™ may be a useful tool for parents to record their infant's symptoms related to feeding and support PCPs in considering CMA in these infants.

摘要

牛奶过敏(CMA)带来了重大的临床负担。牛奶相关症状评分(CoMiSS™)是一种广泛使用的临床筛查工具,旨在提高医疗保健专业人员对CMA的认识。这项定性研究旨在评估家长报告的CoMiSS™工具(Pre-CoMiSS™)的需求,并探讨其对家长和初级保健医生(PCP)的潜在用途。:参与者是年龄在2至12个月的婴儿的家长以及来自德国、瑞典、西班牙和英国(UK)的初级保健医生,他们是从当地潜在受访者小组中挑选出来的。由经验丰富的定性研究主持人进行的访谈包括预先确定的标准化问题。进行了主题分析,并从数据中得出主题。:总共进行了(26)次家长访谈和(18)次初级保健医生访谈。来自所有国家的家长都发现Pre-CoMiSS™工具有助于理解宝宝的症状,易于使用,并且有助于促进与医生的咨询。英国、西班牙和瑞典的医生发现Pre-CoMiSS™工具有助于改善症状报告和医疗咨询;然而,在德国,医生们意见不一,他们担心该工具可能会增加家长的焦虑,导致CMA的过度诊断,并增加他们的工作量。:一种用于记录与牛奶相关症状的家长专用工具总体上受到家长和大多数医生的好评,不过有人指出了对家长焦虑和工作量的担忧,特别是在德国。经过进一步验证和完善,Pre-CoMiSS™可能是一种有用的工具,供家长记录婴儿与喂养相关的症状,并帮助初级保健医生考虑这些婴儿是否患有CMA。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b6f0/12073529/2eaba2bb61cf/nutrients-17-01563-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b6f0/12073529/f76429086201/nutrients-17-01563-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b6f0/12073529/f750031c648b/nutrients-17-01563-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b6f0/12073529/2ab610e80398/nutrients-17-01563-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b6f0/12073529/0d7ab2416c54/nutrients-17-01563-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b6f0/12073529/a352b2ebc3f6/nutrients-17-01563-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b6f0/12073529/2eaba2bb61cf/nutrients-17-01563-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b6f0/12073529/f76429086201/nutrients-17-01563-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b6f0/12073529/f750031c648b/nutrients-17-01563-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b6f0/12073529/2ab610e80398/nutrients-17-01563-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b6f0/12073529/0d7ab2416c54/nutrients-17-01563-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b6f0/12073529/a352b2ebc3f6/nutrients-17-01563-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b6f0/12073529/2eaba2bb61cf/nutrients-17-01563-g006.jpg

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本文引用的文献

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Healthcare (Basel). 2025 Apr 12;13(8):888. doi: 10.3390/healthcare13080888.
2
Parental knowledge and attitudes toward food allergies: a cross-sectional study on determinants and educational needs.家长对食物过敏的认知和态度:一项关于决定因素和教育需求的横断面研究。
BMC Public Health. 2024 Sep 30;24(1):2668. doi: 10.1186/s12889-024-20139-y.
3
Prevalence and risk factors for milk allergy overdiagnosis in the BEEP trial cohort.
BEEP试验队列中牛奶过敏过度诊断的患病率及危险因素。
Allergy. 2025 Jan;80(1):148-160. doi: 10.1111/all.16203. Epub 2024 Jun 20.
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Assessing Feeding Difficulties in Children Presenting with Non-IgE-Mediated Gastrointestinal Food Allergies-A Commonly Reported Problem.评估非 IgE 介导的胃肠道食物过敏儿童的喂养困难——这是一个常见的问题。
Nutrients. 2024 May 22;16(11):1563. doi: 10.3390/nu16111563.
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Diagnosis and management of food allergy-induced constipation in young children-An EAACI position paper.儿童食物过敏相关性便秘的诊断与管理:一项 EAACI 立场文件。
Pediatr Allergy Immunol. 2024 Jun;35(6):e14163. doi: 10.1111/pai.14163.
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World Allergy Organization (WAO) Diagnosis and Rationale for Action against Cow's Milk Allergy (DRACMA) guidelines update - X - Breastfeeding a baby with cow's milk allergy.世界过敏组织(WAO)牛奶过敏诊断与治疗原理(DRACMA)指南更新 - X - 母乳喂养牛奶过敏婴儿。
World Allergy Organ J. 2023 Nov 3;16(11):100830. doi: 10.1016/j.waojou.2023.100830. eCollection 2023 Nov.
7
The Remaining Challenge to Diagnose and Manage Cow's Milk Allergy: An Opinion Paper to Daily Clinical Practice.诊断和管理牛奶过敏的剩余挑战:日常临床实践的观点文件。
Nutrients. 2023 Nov 13;15(22):4762. doi: 10.3390/nu15224762.
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World Allergy Organ J. 2023 Jul 24;16(7):100785. doi: 10.1016/j.waojou.2023.100785. eCollection 2023 Jul.
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