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[Histoautoradiographic study of synthesis of neuronal proteins of the brain in response to exposure to damaging factors during the prenatal period].

作者信息

Kazakova P B, Maĭzelis M Ia, Zabludovskiĭ A L, Orlova M L

出版信息

Zh Nevropatol Psikhiatr Im S S Korsakova. 1985;85(7):1004-6.

PMID:4036420
Abstract

The incorporation of 3H-leucine into the neuronal proteins of the hemispherical cortex and hyppocampus was studied in rats aged 1 and 3 months which were exposed to hypoxia and ethanol in the antenatal period. The test one-month-old animals showed activation of protein synthesis in neurons and in layers III and V of the cortex and hyppocampus. At the age of 3 months the rats showed inhibited incorporation of the label into neuronal proteins of the studied structures of the brain which was more expressed in animals which had suffered intrauterine hypoxia.

摘要

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