Maĭzelis M Ia, Zabludovskiĭ A L
Biull Eksp Biol Med. 1977 Oct;84(10):416-9.
Experiments were conducted on sexually mature rats subjected to acute hypoxia at a definite antenatal period. The penetration of six labeled amino acids into the tissue of different regions of the brain and their incorporation into proteins was studied. Inhibition of protein synthesis especially in the hypothalamus and the cerebral cortex was characteristic of the experimental animals; these findings correlated with disturbances of the conditioned reflex activity. Dysfunction of the blood-brain barrier for labeled amino acids and radioactive phosphorus was found in the experimental animals; as to the permeability of other histohematic barriers -- it was unchanged.
对处于特定孕期且性成熟的大鼠进行急性缺氧实验。研究了六种标记氨基酸在大脑不同区域组织中的渗透情况以及它们掺入蛋白质的情况。实验动物的特征是蛋白质合成受到抑制，尤其是在下丘脑和大脑皮层；这些发现与条件反射活动的紊乱相关。实验动物中发现标记氨基酸和放射性磷的血脑屏障功能障碍；至于其他组织血液屏障的通透性——未发生变化。
