Alrougi Hamoud M, Saqah Rayyan, Khojah Imad, Amer Samar A
General Directorate of Environmental Health, Ministry of Health, Riyadh, Saudi Arabia.
Department of Emergency Medicine, King Abdulaziz University Hospital, Jeddah, Saudi Arabia.
Front Med (Lausanne). 2025 Apr 30;12:1545428. doi: 10.3389/fmed.2025.1545428. eCollection 2025.
This case report describes a case of methanol occupational toxicity in a 44 year-old male ship worker in Jeddah, Saudi Arabia, on 27 August 2024. The patient suddenly lost sight in both eyes and had an unusual acid-base disturbance that was marked by respiratory alkalosis (pH 7.607). This is different from the acidosis that is usually seen in methanol poisoning. Despite aggressive treatment with FOMEPIZOLE, the methanol antidote, and four hemodialysis sessions, the patient's visual prognosis remained poor. This case highlights the potentially devastating consequences of inhalational and contact methanol poisoning and the importance of prompt recognition and treatment, even in the absence of significant neuroimaging findings. It also underscores the need for proper use of personal protective equipment (PPE) in the workplace.
本病例报告描述了2024年8月27日在沙特阿拉伯吉达一名44岁男性船舶工人发生甲醇职业中毒的案例。该患者突然双目失明，并出现以呼吸性碱中毒（pH 7.607）为特征的异常酸碱紊乱。这与甲醇中毒通常所见的酸中毒不同。尽管使用甲醇解毒剂甲吡唑进行了积极治疗，并进行了四次血液透析，但患者的视力预后仍然很差。本病例突出了吸入性和接触性甲醇中毒可能造成的毁灭性后果，以及即使在没有明显神经影像学表现的情况下及时识别和治疗的重要性。它还强调了在工作场所正确使用个人防护装备（PPE）的必要性。
