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甲醇中毒伴双侧视神经炎和中心旁急性黄斑病变

Methanol Intoxication Presenting With Bilateral Optic Neuritis and Paracentral Acute Middle Maculopathy.

作者信息

Saad Sherouk G, Fouad Yousef A, Nowara Mohamed

机构信息

Investigations Unit, Al Mashreq Eye Center, Cairo, EGY.

Ophthalmology, Ain Shams University, Cairo, EGY.

出版信息

Cureus. 2022 Jan 25;14(1):e21587. doi: 10.7759/cureus.21587. eCollection 2022 Jan.

Abstract

A 52-year-old male presented nine days following accidental methanol ingestion with a drop of vision in both eyes. A complete ophthalmic assessment was performed, with a referral to a neurologist for multidisciplinary management. On ophthalmological evaluation, visual acuity was hand motion (HM) bilaterally with swollen optic discs. Macular optical coherence tomography (OCT) showed a picture consistent with paracentral acute middle maculopathy (PAMM) in both eyes, and brain magnetic resonance imaging showed ischemic insults. Slight visual improvement was detected following steroid and antiplatelet therapy. At two months of follow-up, bilateral optic atrophy ensued. Special attention must be given to the macular assessment and not just the optic nerve when considering a case of methanol toxicity, as methanol intoxication can lead to ischemic manifestations.

摘要

一名52岁男性在意外摄入甲醇九天后出现双眼视力下降。进行了全面的眼科评估,并转诊至神经科医生处进行多学科管理。眼科评估显示,双眼视力均为手动(HM),视盘肿胀。黄斑光学相干断层扫描(OCT)显示双眼图像符合中心旁急性黄斑中层病变(PAMM),脑部磁共振成像显示有缺血性损伤。类固醇和抗血小板治疗后视力有轻微改善。随访两个月时,出现双侧视神经萎缩。在考虑甲醇中毒病例时,必须特别关注黄斑评估,而不仅仅是视神经,因为甲醇中毒可导致缺血表现。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f20/8873372/b0512b8d8b4d/cureus-0014-00000021587-i01.jpg

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