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起源不明的腋窝黏液腺癌。

Mucinous adenocarcinoma in the axilla of undetermined origin.

作者信息

Spillane Chloe, Daly Roisin, Cotter Mar, Ylli Kristali, Eljack Wala, Sheehan Ciaran, Girleanu Corina, Bennett Michael, Twomey Aongus

机构信息

Department of Surgery, Mercy University Hospital, Grenville Place, Cork, Ireland, T12 WE28.

Department of Pathology, Cork University Hospital, Wilton, Cork, Ireland, T12 DFK4.

出版信息

J Surg Case Rep. 2025 May 14;2025(5):rjaf258. doi: 10.1093/jscr/rjaf258. eCollection 2025 May.

DOI:10.1093/jscr/rjaf258
PMID:40370952
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12077391/
Abstract

Mucinous adenocarcinoma (MAC), accounts for ⁓1% of all cancer diagnoses. We present a case of a 75-year-old male who, after presenting for an elective inguinal hernia repair, disclosed concerns for a new lesion in his right axilla which was removed at the same time. Investigations revealed a MAC of unclear origin, with immunohistochemistry suggesting either a breast or primary cutaneous mucinous adenocarcinoma (PCMC). The patient was asymptomatic with an otherwise normal examination. Extensive investigations failed to identify any primary source. Axillary node clearance was performed, resulting in 0/9 positive nodes. After multi-disciplinary team discussion, this patient (who remains asymptomatic) will be kept under close clinical surveillance, with yearly computerized tomography scans. To our knowledge, minimal presentations have been reported in the literature. Thus, our case report is a unique addition of an atypical presentation of PCMC in the axilla.

摘要

黏液腺癌(MAC)占所有癌症诊断病例的约1%。我们报告一例75岁男性病例,该患者因择期腹股沟疝修补术就诊,同时发现右腋窝有一新病灶并予以切除。检查发现起源不明的MAC,免疫组化提示可能为乳腺或原发性皮肤黏液腺癌(PCMC)。患者无症状,其他检查均正常。广泛检查未能发现任何原发灶。行腋窝淋巴结清扫术,结果9个淋巴结均为阴性。经多学科团队讨论,该无症状患者将接受密切临床监测,每年进行计算机断层扫描。据我们所知,文献中报道的此类病例极少。因此,我们的病例报告是PCMC在腋窝非典型表现的独特补充。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/38a8/12077391/92460ad2f5da/rjaf258f6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/38a8/12077391/ba9d1402adb0/rjaf258f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/38a8/12077391/d9c53c21f274/rjaf258f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/38a8/12077391/1db16743d9af/rjaf258f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/38a8/12077391/65c433dd44cf/rjaf258f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/38a8/12077391/8bba4fb87396/rjaf258f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/38a8/12077391/92460ad2f5da/rjaf258f6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/38a8/12077391/ba9d1402adb0/rjaf258f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/38a8/12077391/d9c53c21f274/rjaf258f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/38a8/12077391/1db16743d9af/rjaf258f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/38a8/12077391/65c433dd44cf/rjaf258f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/38a8/12077391/8bba4fb87396/rjaf258f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/38a8/12077391/92460ad2f5da/rjaf258f6.jpg

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本文引用的文献

1
Primary Cutaneous Mucinous Carcinoma Monitoring: A Role for CA15.3 and CEA?原发性皮肤黏液癌的监测:CA15.3和癌胚抗原的作用?
Case Rep Oncol. 2022 Dec 21;15(3):1114-1119. doi: 10.1159/000525524. eCollection 2022 Sep-Dec.
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Epidemiology of Mucinous Adenocarcinomas.黏液腺癌的流行病学
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Analysis of Head and Neck Primary Cutaneous Mucinous Carcinoma: An Indolent Tumor of the Eccrine Sweat Glands.头颈部原发性皮肤黏液腺癌分析:一种源于外分泌汗腺的惰性肿瘤。
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Eplasty. 2013 Jun 18;13:ic47. Print 2013.
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