Krämer J, Lenz W, Viebahn A, Brandis H
Zentralbl Bakteriol Orig A. 1977;237(2-3):318-23.
Purified enterocin E1A, a bacteriocin produced by Streptococcus faecium E1, had a strong bactericidal activity on susceptible cells of Listeria monocytogenes. Electronmicroscopic observation of thin sections of L. monocytogenes, treated with enterocin E1A at a concentration that gave 0.1% survivors, revealed that the predominant features of morphological alterations concern the partial dissolution of the cell content and the damage of the cell envelope which enabled an efflux of cell-material. Not frequently intact protoplasts and greatly elongated cells were observed.
纯化后的屎肠球菌E1产生的细菌素肠球菌素E1A,对单核细胞增生李斯特菌的敏感细胞具有很强的杀菌活性。用肠球菌素E1A处理单核细胞增生李斯特菌,浓度为使存活率达到0.1%,对其超薄切片进行电子显微镜观察发现,形态改变的主要特征是细胞内容物部分溶解以及细胞膜受损,导致细胞物质外流。偶尔也会观察到完整的原生质体和极度伸长的细胞。