Sun Hongbing
Department of Earth and Chemical Sciences, Rider University, 2083 Lawrenceville Road, Lawrenceville, NJ, 08648, USA.
J Racial Ethn Health Disparities. 2025 May 15. doi: 10.1007/s40615-025-02480-z.
Nutritional rickets is disproportionately prevalent among African American children and is closely linked to vitamin D (VD) deficiency. This study aims to analyze the prevalence and trends of vitamin D deficiency in American children, as well as pregnant and lactating women, from 2001 to 2023, with a focus on African American children.
We analyzed serum 25(OH)D levels from 2001 to 2023, as well as dietary and supplemental vitamin D intake from 2007 to 2020, among children aged 1-17 years and pregnant and lactating women. Data were from the US National Health and Nutrition Examination Survey.
In the 2021-2023 sample, African American children had the highest rate of severe 25(OH)D deficiency (< 25 nmol/L) at 13.8% among all racial groups. This represents a significant increase from 5% in 2001-2002. Additionally, 2% of African American toddlers aged 12-23 months had severely deficient 25(OH)D levels between 2003 and 2023. An increase in severe 25(OH)D deficiency was also observed in pregnant and lactating African American women during the 2021-2023 period. Furthermore, 83.3% of African American children and 61.4% of pregnant and lactating African American women had daily vitamin D intakes below 10 mcg (400 IU), the highest inadequacy rates among all racial groups from 2007 to 2020.
The recent rise in severe vitamin D deficiency among African American children, pregnant, and lactating women increases the risk of nutritional rickets and calls for prompt public health attention.
营养性佝偻病在非裔美国儿童中极为普遍，且与维生素D（VD）缺乏密切相关。本研究旨在分析2001年至2023年美国儿童以及孕妇和哺乳期妇女中维生素D缺乏的患病率及趋势，重点关注非裔美国儿童。
我们分析了2001年至2023年1至17岁儿童以及孕妇和哺乳期妇女的血清25(OH)D水平，以及2007年至2020年的膳食和补充维生素D摄入量。数据来自美国国家健康与营养检查调查。
在2021 - 2023年的样本中，非裔美国儿童在所有种族群体中严重25(OH)D缺乏（<25 nmol/L）率最高，为13.8%。这相较于2001 - 2002年的5%有显著增加。此外，在2003年至2023年期间，2%的12至23个月大的非裔美国幼儿25(OH)D水平严重不足。在2021 - 2023年期间，非裔美国孕妇和哺乳期妇女中严重25(OH)D缺乏情况也有所增加。此外，在2007年至2020年期间，83.3%的非裔美国儿童和61.4%的非裔美国孕妇和哺乳期妇女每日维生素D摄入量低于10 mcg（400 IU），是所有种族群体中不足率最高的。
近期非裔美国儿童、孕妇和哺乳期妇女中严重维生素D缺乏情况的增加，增加了营养性佝偻病的风险，需要公共卫生部门迅速关注。
