Department of Ophthalmology, Tsukazaki Hospital, Himeji, Japan.
Department of Technology and Design Thinking for Medicine, Hiroshima University Graduate School of Biomedical and Health Sciences, Hiroshima, Japan.
Sci Rep. 2024 Mar 4;14(1):5292. doi: 10.1038/s41598-024-55926-5.
To evaluate the visual performance of a diffractive bifocal intraocular lens (IOL) with + 4.0 D near addition (ZMB00) and a diffractive trifocal IOL with + 2.17 D and + 3.25 D near addition (AcrySof IQ PanOptix TFNT00), we investigated the 10-week postoperative parameters after cataract surgery in which ZMB00 or TFNT00 lenses were implanted bilaterally from 2011 to 2020 (with a 3-month interval between implantation of the right and left lenses). The study included 1448 eyes of 724 patients. The diffractive bifocal group comprised 1326 eyes of 663 patients (aged 67.0 ± 7.8 years; females/males, 518/145), and the diffractive trifocal group comprised 122 eyes of 61 patients (aged 66.6 ± 7.3 years; females/males, 35/26). A linear mixed-effects model using data for both eyes, with strict adjustments for sex, age, subjective refraction spherical equivalent, subjective refraction cylinder, corneal astigmatism, axial length, corneal higher-order aberrations, and pupil diameter, ensured statistical validity. Uncorrected near visual acuity and higher-order aberrations (ocular/internal, scaled to a pupil size of 4 mm) (Wavefront_4mm_postoperative_Ocular/Internal_Spherical) were significantly better in the bifocal group (p < 0.00068, Wald test). Uncorrected intermediate visual acuity, contrast sensitivity (6.3/4.0/2.5/1.6/1.0/0.7 degrees), and contrast sensitivity with glare (4.0/1.6/1.0/0.7 degrees) were significantly better in the trifocal group (p < 0.00068, Wald test).
为了评估 +4.0 D 近附加（ZMB00）的衍射双焦点人工晶状体（IOL）和 +2.17 D 和 +3.25 D 近附加（AcrySof IQ PanOptix TFNT00）的衍射三焦点 IOL 的视觉性能，我们调查了 2011 年至 2020 年期间白内障手术后 10 周的术后参数，在此期间，双侧植入了 ZMB00 或 TFNT00 晶状体（右眼和左眼植入之间间隔 3 个月）。研究包括 724 名患者的 1448 只眼。衍射双焦点组包括 663 名患者的 1326 只眼（年龄 67.0 ± 7.8 岁；女性/男性，518/145），和衍射三焦点组包括 61 名患者的 122 只眼（年龄 66.6 ± 7.3 岁；女性/男性，35/26）。使用双眼数据的线性混合效应模型，对性别、年龄、主观屈光球镜等效物、主观屈光柱镜、角膜散光、眼轴、角膜高阶像差和瞳孔直径进行严格调整，确保了统计有效性。未矫正的近视力和高阶像差（眼内/眼内，校正到 4mm 瞳孔大小）（Wavefront_4mm_postoperative_Ocular/Internal_Spherical）在双焦点组中显著更好（p<0.00068，Wald 检验）。未矫正的中间视力、对比敏感度（6.3/4.0/2.5/1.6/1.0/0.7 度）和眩光下的对比敏感度（4.0/1.6/1.0/0.7 度）在三焦点组中显著更好（p<0.00068，Wald 检验）。
