Ogannisyan Mkrtych, Slivin Anton, LeBaron Tyler W, Tarnava Alex, Karmazin Valeriy, Bazanovich Sergey, Dolgachev Vladislav, Vychik Anna, Strizhkov Alexander, Parastaev Sergey
Federal Research and Clinical Center of Sports Medicine and Rehabilitation of Federal Medical Biological Agency, Moscow, Russia.
Department of Rehabilitation, Sports Medicine, and Physical Culture, Pirogov Russian National Research Medical University, Moscow, Russia.
J Lifestyle Med. 2025 Feb 28;15(1):8-17. doi: 10.15280/jlm.2025.15.1.8.
Physical activity significantly increases the production of reactive oxygen species in the body. Molecular hydrogen has been shown to have safe and effective antioxidant properties on athletes. However, research on elite athletes is scarce.
A randomized, double-blinded, placebo-controlled trial was conducted with 22 female elite athletes participating in handball and skeleton sports. The first group received hydrogen-rich water (HRW)-generating tablets, whereas the second group consumed a visually and organoleptically similar placebo. Various assessments were performed during HRW intake, such as anthropometric and biochemical measurements, stress, and recovery parameters, as well as biomechanical testing.
HRW consumption resulted inan increase in muscle mass and a reduction in fat mass (p < 0.05). However, HRW did not significantly affect stress or recovery rates, as determined by the Recovery-Stress Questionnaire-Sport questionnaire. However, the HRW group exhibited a significant increase in torque, particularly after an intensive exercise test (p < 0.05). Moreover, HRW intake led to a reduction in total creatine kinase, vitamin C, and beta-carotene contents (p < 0.05), whereas the vitamin E and interleukin-10 levels increased compared with baseline levels (p < 0.05).
The HRW-generating tablets were found to be safe and well-tolerated by the participants. These tablets also exerted ergogenic effects by reducing body fat percentage, increasing muscle mass percentage, improving maximal torque, decreasing muscle damage, and positively modulating the exercise-induced inflammatory and antioxidant responses to exercise. Although the mechanism of action of HRW remains unclear, these effects observed indicate its potential for diverse applications in high-performance sports.
体育活动会显著增加体内活性氧的产生。分子氢已被证明对运动员具有安全有效的抗氧化特性。然而，针对精英运动员的研究却很匮乏。
进行了一项随机、双盲、安慰剂对照试验，22名参与手球和雪橇运动的女性精英运动员参与其中。第一组服用产富氢水（HRW）的片剂，而第二组服用外观和感官相似的安慰剂。在摄入HRW期间进行了各种评估，如人体测量和生化测量、压力和恢复参数，以及生物力学测试。
饮用HRW导致肌肉量增加和脂肪量减少（p<0.05）。然而，根据恢复 - 压力问卷 - 运动问卷的结果，HRW对压力或恢复率没有显著影响。不过，HRW组的扭矩显著增加，尤其是在高强度运动测试后（p<0.05）。此外，摄入HRW导致总肌酸激酶、维生素C和β-胡萝卜素含量降低（p<0.05），而维生素E和白细胞介素-10水平与基线水平相比有所升高（p<0.05）。
发现产HRW的片剂对参与者来说是安全且耐受性良好的。这些片剂还通过降低体脂百分比、增加肌肉质量百分比、提高最大扭矩、减少肌肉损伤以及积极调节运动引起的炎症和抗氧化反应，发挥了促力作用。尽管HRW的作用机制尚不清楚，但观察到的这些效果表明其在高性能运动中有多种应用潜力。
