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在循环保留和缺血条件下对犬胰腺组织pH值进行电测。

Electrometric measurement of canine pancreatic tissue pH under conditions of preserved circulation and of ischaemia.

作者信息

Farkas S, Lantos L, Halmágyi G, Gecser G, Ezer P

出版信息

Acta Med Acad Sci Hung. 1978;35(3-4):287-97.

PMID:40377
Abstract

Canine pancreatic pH was measured by an electrometric method, which is described in detail. 60 measurements carried out in neuroleptanalgesia of the animals gave a mean figure of 7.29 +/- 0.10 for pancreatic pH in situ. For arterial blood pH in the same animals the mean value was 7.22 +/- 0.08. The difference between pancreatic and arterial blood pH is significant. Anaesthesia of 3 hr duration produced no significant change either in pancreatic pH or in arterial blood pH or in the serum amylase and serum lipase levels. Vascular isolation of the pancreas and adjoining duodenal segment was produced in 13 animals. In 10 of these ischaemia induced by clamping of the arterial pathways for 1 hr resulted in a fall of pH by 0.65 +/- 0.21. Restoration of blood-flow at the end of the first hour was followed by a return of pH to the original values. The 3 control animals revealed no significant changes in the pH and enzyme values.

摘要

采用一种已详细描述的电位测量法来测量犬胰腺的pH值。对动物进行神经安定镇痛时进行的60次测量得出,胰腺原位pH值的平均数值为7.29±0.10。同一批动物动脉血pH值的平均值为7.22±0.08。胰腺pH值与动脉血pH值之间的差异具有统计学意义。持续3小时的麻醉对胰腺pH值、动脉血pH值以及血清淀粉酶和血清脂肪酶水平均未产生显著影响。对13只动物进行了胰腺及相邻十二指肠段的血管分离。其中10只动物通过夹闭动脉通路1小时诱导缺血,导致pH值下降0.65±0.21。在第一小时末恢复血流后,pH值恢复到原始值。3只对照动物的pH值和酶值未显示出显著变化。

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