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超声引导下皮肤癌转移灶术中定位的新技术:一例报告

Novel technique in intraoperative localisation of skin cancer metastasis using ultrasound guidance: a case report.

作者信息

Hawwash Nadin, Fadel Amr, Bista Niranjan, Mullan Damian, Kosutic Damir

机构信息

School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.

Cancer Research UK Manchester Cancer Research Centre, Manchester, UK.

出版信息

Discov Oncol. 2025 May 16;16(1):778. doi: 10.1007/s12672-025-02463-w.

Abstract

BACKGROUND

Localisation of metastatic squamous cell carcinoma (SCC) often poses intraoperative challenges. There is limited description of surgical practices to address these difficulties in the literature. Low-frequency ultrasound use intraoperatively may enhance tumour detection and facilitate complete resection.

CASE PRESENTATION

We present the case of a 78-year-old male with right-sided intra-parotid metastatic SCC requiring surgical excision. This was completed under intraoperative ultrasound scan guidance. Preoperative whole-body PET-CT and MRI of the head were inadequate for confirming accurate lesion localisation regarding the depth of invasion and facial nerve involvement. Intraoperative ultrasound performed by a consultant radiologist guided the metastasectomy by confirming lesion boundaries, navigating safe excision by sparing the facial nerve branches and facilitating the avoidance of more radical resection. Full resection with no residual disease was confirmed intraoperatively with the ultrasound.

CONCLUSION

We propose using ultrasound guidance intraoperatively to aid localisation and excision of metastatic disease in anatomically challenging sites.

摘要

背景

转移性鳞状细胞癌(SCC)的定位在术中常常带来挑战。文献中针对解决这些困难的手术操作描述有限。术中使用低频超声可能会提高肿瘤的检出率并有助于完整切除。

病例介绍

我们报告一例78岁男性患者,其右侧腮腺内有转移性SCC,需要进行手术切除。手术在术中超声扫描引导下完成。术前的全身PET-CT和头部MRI对于确定病变关于侵犯深度和面神经受累情况的准确位置并不充分。由放射科顾问医生进行的术中超声通过确认病变边界来指导转移瘤切除术,通过保留面神经分支来引导安全切除,并有助于避免更激进的切除。术中超声确认实现了无残留疾病的完整切除。

结论

我们建议术中使用超声引导,以辅助在解剖结构复杂部位的转移性疾病的定位和切除。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f80/12084446/9632bc68ca0e/12672_2025_2463_Fig1_HTML.jpg

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