Iversen O J, Rødahl E
Arch Virol. 1985;86(1-2):37-45. doi: 10.1007/BF01314112.
The major internal protein, p27, of a retrovirus-like particle isolated from the urine of a patient with psoriasis has been purified and used in an indirect ELISA to detect human antibodies against the virus antigen. Rabbit anti-p27 antiserum has been applied to detect p27 antigen present in clinical specimens. p27 and anti-p27 antibodies have been demonstrated in extracts from psoriatic scales. Insignificant amounts of free anti-p27 antibodies are present in serum, but both p27 and anti-p27 antibodies have been detected in circulating immune complexes obtained from serum or synovial fluid from patients with psoriatic arthritis.
从一名银屑病患者尿液中分离出的类逆转录病毒颗粒的主要内部蛋白p27已被纯化，并用于间接酶联免疫吸附测定（ELISA）以检测人类针对该病毒抗原的抗体。兔抗p27抗血清已用于检测临床标本中存在的p27抗原。在银屑病鳞屑提取物中已证实存在p27和抗p27抗体。血清中存在少量游离抗p27抗体，但在银屑病关节炎患者血清或滑液中获得的循环免疫复合物中已检测到p27和抗p27抗体。
