大鼠皮肤钙结合蛋白是小白蛋白。
Rat skin calcium-binding protein is parvalbumin.
作者信息
MacManus J P, Watson D C, Yaguchi M
出版信息
Biochem J. 1985 Jul 1;229(1):39-45. doi: 10.1042/bj2290039.
Abstract
Only one major low-Mr calcium-binding protein could be isolated by h.p.l.c. procedures from aqueous extracts of homogenized adult rat skin. This was shown by tryptic peptide mapping and independent amino acid sequence analysis to be identical in all 109 residues with the parvalbumin from rat skeletal muscle. This calcium-binding protein was not in skin epidermis, but was confined to the dermal layer. Skin calcium-binding protein is therefore parvalbumin.
摘要
通过高效液相色谱法（h.p.l.c.）程序，仅能从成年大鼠皮肤匀浆的水提取物中分离出一种主要的低分子量钙结合蛋白。经胰蛋白酶肽图谱分析和独立的氨基酸序列分析表明，该蛋白在所有109个残基上与大鼠骨骼肌中的小白蛋白完全相同。这种钙结合蛋白不在皮肤表皮中，而是局限于真皮层。因此，皮肤钙结合蛋白就是小白蛋白。
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