• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

耐药性研究热点的文献计量分析。

Bibliometric analysis of hotspots in drug resistance research.

作者信息

Shi Jianguo

机构信息

Department of Clinical Laboratory, First Hospital of Shanxi Medical University, Taiyuan, Shanxi, China.

出版信息

Front Microbiol. 2025 May 2;16:1572400. doi: 10.3389/fmicb.2025.1572400. eCollection 2025.

DOI:10.3389/fmicb.2025.1572400
PMID:40384786
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12082710/
Abstract

OBJECTIVE

Bibliometric analysis was used to visualize the current literature data on drug resistance.

METHODS

We used a bibliometrix package that utilizes R 4.4.1, all drug resistance related research literature in the WOS core database, and data visualization and analysis of the retrieved research literature.

RESULTS

A total of 3,253 research articles on resistance were screened, and the number of publications related to resistance is increasing year by year. China ranks first in the number of publications, and the United States ranks first in terms of citations. Frontiers in microbiology has published the most articles on this research topic. Wang Y, Lee JH, and Simoes M have published the most articles, and Franci G has the most citations. The Egyptian Knowledge Bank (EKB), the Chinese Academy of Sciences, and Harvard University are the main research institutes. A total of 15,824 authors have contributed to the field, with the majority of authors coming from China, followed by South Korea and the United States, and most of them coming from the Chinese Academy of Science and Jilin University. The mechanism of drug resistance in was the most important research hotspot, with coming up 984 times, (10%), followed by antibiotic-resistance (693 times, 7%) and biofilm formation (517 times, 5%).

CONCLUSION

This study comprehensively summarizes past research trends in resistance and identifies the countries, institutions, authors, journals, and publications involved in this field. The results provide a comprehensive overview of the study of resistance in .

摘要

目的

采用文献计量分析方法可视化当前关于耐药性的文献数据。

方法

我们使用了一个利用R 4.4.1的文献计量软件包，检索了Web of Science核心数据库中所有与耐药性相关的研究文献，并对检索到的研究文献进行数据可视化和分析。

结果

共筛选出3253篇关于耐药性的研究文章，与耐药性相关的出版物数量逐年增加。中国的出版物数量排名第一，美国在被引频次方面排名第一。《微生物学前沿》发表的关于该研究主题的文章最多。王Y、李JH和西莫斯M发表的文章最多，弗兰奇G的被引频次最高。埃及知识银行（EKB）、中国科学院和哈佛大学是主要的研究机构。共有15824位作者为该领域做出了贡献，大多数作者来自中国，其次是韩国和美国，他们大多来自中国科学院和吉林大学。[此处原文有缺失信息，推测为某一具体研究对象]的耐药机制是最重要的研究热点，出现了984次（10%），其次是抗生素耐药性（693次，7%）和生物膜形成（517次，5%）。

结论

本研究全面总结了过去[此处原文有缺失信息，推测为某一具体研究对象]耐药性的研究趋势，并确定了该领域涉及的国家、机构、作者、期刊和出版物。研究结果提供了对[此处原文有缺失信息，推测为某一具体研究对象]耐药性研究的全面概述。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47f8/12082710/bcd454a4b21e/fmicb-16-1572400-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47f8/12082710/166ab12ae0f3/fmicb-16-1572400-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47f8/12082710/96e32a1694d1/fmicb-16-1572400-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47f8/12082710/00099b40b24d/fmicb-16-1572400-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47f8/12082710/0ce988436b51/fmicb-16-1572400-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47f8/12082710/66f7a3c29d7b/fmicb-16-1572400-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47f8/12082710/d1d5b2e42504/fmicb-16-1572400-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47f8/12082710/27de8b4bfd5c/fmicb-16-1572400-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47f8/12082710/bcd454a4b21e/fmicb-16-1572400-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47f8/12082710/166ab12ae0f3/fmicb-16-1572400-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47f8/12082710/96e32a1694d1/fmicb-16-1572400-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47f8/12082710/00099b40b24d/fmicb-16-1572400-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47f8/12082710/0ce988436b51/fmicb-16-1572400-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47f8/12082710/66f7a3c29d7b/fmicb-16-1572400-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47f8/12082710/d1d5b2e42504/fmicb-16-1572400-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47f8/12082710/27de8b4bfd5c/fmicb-16-1572400-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47f8/12082710/bcd454a4b21e/fmicb-16-1572400-g008.jpg

相似文献

1
Bibliometric analysis of hotspots in drug resistance research.耐药性研究热点的文献计量分析。
Front Microbiol. 2025 May 2;16:1572400. doi: 10.3389/fmicb.2025.1572400. eCollection 2025.
2
The published role of artificial intelligence in drug discovery and development: a bibliometric and social network analysis from 1990 to 2023.人工智能在药物发现与开发中的已发表作用：1990年至2023年的文献计量学与社会网络分析
J Cheminform. 2025 May 8;17(1):71. doi: 10.1186/s13321-025-00988-4.
3
Research hotspots and frontiers of machine learning in renal medicine: a bibliometric and visual analysis from 2013 to 2024.肾脏医学中机器学习的研究热点与前沿：2013年至2024年的文献计量学与可视化分析
Int Urol Nephrol. 2025 Mar;57(3):907-928. doi: 10.1007/s11255-024-04259-3. Epub 2024 Oct 30.
4
Knowledge domain and hotspots concerning photosensitive hydrogels for tissue engineering applications: A bibliometric and visualized analysis (1996-2022).用于组织工程应用的光敏水凝胶的知识领域与热点：文献计量学与可视化分析（1996 - 2022）
Front Bioeng Biotechnol. 2022 Nov 14;10:1067111. doi: 10.3389/fbioe.2022.1067111. eCollection 2022.
5
Current perspectives and trends of CD39-CD73-eAdo/A2aR research in tumor microenvironment: a bibliometric analysis.肿瘤微环境中 CD39-CD73-eAdo/A2aR 研究的现状和趋势：文献计量学分析。
Front Immunol. 2024 Aug 12;15:1427380. doi: 10.3389/fimmu.2024.1427380. eCollection 2024.
6
[Research hot spots and trends of keratoconus in China: a bibliometric analysis].[中国圆锥角膜的研究热点与趋势：文献计量学分析]
Zhonghua Yan Ke Za Zhi. 2024 Feb 11;60(2):156-167. doi: 10.3760/cma.j.cn112142-20231009-00126.
7
Global Highly Cited Publication Trends and Research Hotspots in Osteoporosis and Bone Metabolic Cells: A Bibliometric and Visualization Analysis from 2013 to 2023.骨质疏松症与骨代谢细胞领域的全球高被引出版物趋势及研究热点：2013年至2023年的文献计量学与可视化分析
Endocr Metab Immune Disord Drug Targets. 2025;25(5):386-399. doi: 10.2174/0118715303300989240702043834.
8
A Bibliometric and Knowledge-Map Analysis of Macrophage Polarization in Insulin Resistance From 1999 to 2023.从 1999 年到 2023 年，胰岛素抵抗中巨噬细胞极化的文献计量学和知识图谱分析
Immun Inflamm Dis. 2024 Oct;12(10):e70048. doi: 10.1002/iid3.70048.
9
Mapping the Evolution of Digital Health Research: Bibliometric Overview of Research Hotspots, Trends, and Collaboration of Publications in JMIR (1999-2024).绘制数字健康研究的演进图：JMIR（1999-2024 年）研究热点、趋势和出版物合作的文献计量学概述。
J Med Internet Res. 2024 Oct 17;26:e58987. doi: 10.2196/58987.
10
Knowledge Mapping of Macrophages in Osteoporosis: A Bibliometric Analysis (1999-2023).骨质疏松症中巨噬细胞的知识图谱：文献计量分析（1999-2023）。
Orthop Surg. 2024 Oct;16(10):2326-2343. doi: 10.1111/os.14159. Epub 2024 Jul 9.

本文引用的文献

1
Host Spectrum Correlates with Methicillin Resistance in a Multi-Species Ecosystem.宿主谱与多物种生态系统中的耐甲氧西林特性相关。
Microorganisms. 2023 Feb 3;11(2):393. doi: 10.3390/microorganisms11020393.
2
Molecular Mechanisms of Drug Resistance in .肿瘤多药耐药相关基因的分子机制研究进展
Int J Mol Sci. 2022 Jul 22;23(15):8088. doi: 10.3390/ijms23158088.
3
Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis.2019 年全球细菌对抗菌药物耐药性的负担：系统分析。
Lancet. 2022 Feb 12;399(10325):629-655. doi: 10.1016/S0140-6736(21)02724-0. Epub 2022 Jan 19.
4
The Prevalence and Determinants of Fusidic Acid Resistance Among Methicillin-Resistant Clinical Isolates in China.中国耐甲氧西林临床分离株中夫西地酸耐药性的流行情况及影响因素
Front Med (Lausanne). 2021 Nov 30;8:761894. doi: 10.3389/fmed.2021.761894. eCollection 2021.
5
Biochanin A as an α-hemolysin inhibitor for combating methicillin-resistant Staphylococcus aureus infection.染料木黄酮 A 作为一种抗 α-溶血素抑制剂，用于治疗耐甲氧西林金黄色葡萄球菌感染。
World J Microbiol Biotechnol. 2021 Nov 27;38(1):6. doi: 10.1007/s11274-021-03182-4.
6
Synergism of a Novel 1,2,4-oxadiazole-containing Derivative with Oxacillin against Methicillin-Resistant .一种含新型1,2,4-恶二唑的衍生物与苯唑西林对耐甲氧西林菌的协同作用
Antibiotics (Basel). 2021 Oct 16;10(10):1258. doi: 10.3390/antibiotics10101258.
7
Bacteriophage Rescue Therapy of a Vancomycin-Resistant Infection in a One-Year-Old Child following a Third Liver Transplantation.经第三次肝移植后，一岁儿童万古霉素耐药感染的噬菌体拯救治疗。
Viruses. 2021 Sep 7;13(9):1785. doi: 10.3390/v13091785.
8
Therapeutic Strategies To Counteract Antibiotic Resistance in MRSA Biofilm-Associated Infections.治疗耐甲氧西林金黄色葡萄球菌生物膜相关感染的抗生素耐药性的策略。
ChemMedChem. 2021 Jan 8;16(1):65-80. doi: 10.1002/cmdc.202000677. Epub 2020 Nov 6.
9
Antimicrobial Resistance in ESKAPE Pathogens.ESKAPE 病原体中的抗微生物药物耐药性。
Clin Microbiol Rev. 2020 May 13;33(3). doi: 10.1128/CMR.00181-19. Print 2020 Jun 17.
10
Methicillin-resistant (MRSA): antibiotic-resistance and the biofilm phenotype.耐甲氧西林金黄色葡萄球菌（MRSA）：抗生素耐药性与生物被膜表型
Medchemcomm. 2019 Mar 14;10(8):1231-1241. doi: 10.1039/c9md00044e. eCollection 2019 Aug 1.