Gu Yafeng, Wu Huizhen, Tian Weiling, Jiang Hailin, Huang Liyu, Liu Hongchao, Liao Huaqiang, Meng Xiaoxi, Dong Weihua
Department of Interventional Radiology, The Second Affiliated Hospital of the Naval Medical University of the Chinese People's Liberation Army, Shanghai, China.
Department of General Practice, Xinhua Hospital, Jiao Tong University School of Medicine, Shanghai, China.
Sci Prog. 2025 Apr-Jun;108(2):368504251344186. doi: 10.1177/00368504251344186. Epub 2025 May 19.
Acute hemorrhagic rectal ulcer (AHRU), though a relatively rare etiology of lower gastrointestinal bleeding, represents a critical clinical emergency characterized by sudden onset, painless, massive, and fresh rectal bleeding. While endoscopic hemostasis remains prominent therapy, its efficacy is limited in emergency settings by poor bowel preparation and obscured visualization. Rectal arterial embolization (RAE) offers a viable alternative, however, detailed descriptions of its application for AHRU in literature are lacking. Thus, we report a single-center experience of RAE in six patients with massive AHRU-related bleeding. Technical success was achieved in 83% (5/6) of cases, with clinical success was achieved in 100% cases (6/6). Rebleeding after initial RAE procedure occurred in 33% (2/6) of cases, one of which ultimately achieving hemostasis through transanal suturing after initial embolization failure. No major embolism-related complications were observed during follow-up. Moreover, complete embolization of rectal supplies demonstrated potential to reduce rebleeding risk, and empiric embolization may hold promise for managing refractory AHRU hemorrhage. These findings advocate for RAE as an effective alternative for AHRU hemorrhage, though further validation in larger cohorts is essential.
急性出血性直肠溃疡(AHRU)虽然是下消化道出血相对少见的病因,但却是一种危急的临床急症,其特征为突然发作、无痛、大量且新鲜的直肠出血。虽然内镜止血仍然是主要治疗方法,但其疗效在紧急情况下因肠道准备不佳和视野不清而受到限制。直肠动脉栓塞术(RAE)提供了一种可行的替代方法,然而,文献中缺乏其用于AHRU的详细描述。因此,我们报告了单中心对6例AHRU相关大量出血患者进行RAE的经验。83%(5/6)的病例技术成功,100%(6/6)的病例临床成功。初次RAE术后33%(2/6)的病例发生再出血,其中1例在初次栓塞失败后最终通过经肛门缝合实现止血。随访期间未观察到与栓塞相关的重大并发症。此外,直肠供血的完全栓塞显示出降低再出血风险的潜力,经验性栓塞可能有望治疗难治性AHRU出血。这些发现支持RAE作为AHRU出血的有效替代方法,尽管在更大队列中进行进一步验证至关重要。