Ndiokwelu Chibuzo Obiora, Okoro Chinonso Bismark, Nwachukwu Paul Tochukwu, Odimegwu Chioma Laura, Uwaezuoke Samuel Nkachukwu
Department of Paediatrics, University of Nigeria Teaching Hospital, Ituku-Ozalla, Enugu State, Nigeria.
Department of Microbiology, University of Nigeria Teaching Hospital, Ituku-Ozalla, Enugu State, Nigeria.
BMC Infect Dis. 2025 May 19;25(1):720. doi: 10.1186/s12879-025-11053-8.
Norwegian scabies, also known as crusted scabies, is a severe form of scabies caused by an infestation of the skin by the Sarcoptes scabiei var. hominis mite. It is usually diagnostically challenging because of its rare nature and the potential for misdiagnosis with other skin diseases. This case report presents a rare case of Norwegian scabies seen at the University of Nigeria Teaching Hospital, Ituku-Ozalla, Enugu State.
The patient, a 16-year-old male Human Immunodeficiency Virus (HIV) positive patient, diagnosed with HIV 2 years before presentation but was not adherent to his Anti-retroviral medications, presented with extensive crusted lesions covering the entire body. CD4 + count on admission was 54 cells/mm and the viral load was 604 copies/ml and the initial clinical diagnosis was seborrheic hyperkeratosis. The diagnosis was eventually confirmed through skin scrapings and microscopic examination. The patient was then treated with oral ivermectin, topical scabicidal agents, antibiotics, antihistamines, and emollients, with complete clearance of lesions noted after two weeks of treatment.
This case highlights the importance of recognizing and promptly treating this apparently rare and diagnostically challenging skin condition in Nigeria.
挪威疥疮,又称结痂性疥疮,是由人疥螨感染皮肤引起的一种严重疥疮形式。由于其罕见性以及与其他皮肤病混淆误诊的可能性,其诊断通常具有挑战性。本病例报告展示了在尼日利亚埃努古州伊图库 - 奥扎拉的尼日利亚大学教学医院所见到的一例罕见的挪威疥疮病例。
该患者为一名16岁男性,人类免疫缺陷病毒(HIV)阳性,在就诊前2年被诊断出感染HIV,但未坚持服用抗逆转录病毒药物,全身出现广泛的结痂性皮损。入院时CD4 +细胞计数为54个细胞/mm,病毒载量为604拷贝/ml,初步临床诊断为脂溢性角化病。最终通过皮肤刮片和显微镜检查确诊。随后患者接受了口服伊维菌素、外用杀疥剂、抗生素、抗组胺药和润肤剂治疗,治疗两周后皮损完全消退。
本病例凸显了在尼日利亚认识并及时治疗这种明显罕见且诊断具有挑战性的皮肤病的重要性。