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剖宫产术中三种皮肤缝合技术的比较(可吸收皮下缝合线、不可吸收尼龙缝合线、手术吻合器):一项随机对照试验。

Comparison of Three Techniques for Skin Closure in Caesarean Delivery (Absorbable Subcuticular Sutures, Non-absorbable Nylon Sutures, Surgical Staplers): A Randomized Controlled Trial.

作者信息

Kushwaha Shreya S, Singhal Seema, Dhiman Soniya, Kumar Sunesh, Roy Kallol K, Meena Jyoti, Tomar Swati

机构信息

Department of Obstetrics and Gynaecology, All India Institute of Medical Sciences, New Delhi, 110029 India.

Present Address: Division of Maternal and Fetal Medicine, Department of Obstetrics and Gynaecology, VMMC and Safdarjung Hospital, New Delhi, India.

出版信息

J Obstet Gynaecol India. 2025 Apr;75(Suppl 1):348-354. doi: 10.1007/s13224-024-01999-1. Epub 2024 Jun 13.

Abstract

BACKGROUND

Caesarean section is associated with post-operative surgical complications such as wound disruption, induration and hematoma. It is essential to optimize surgical techniques to ensure the best possible outcomes for women undergoing caesarean section.

METHODS

This was a randomized controlled trial done at a tertiary care centre. A total of 300 women undergoing first caesarean section were randomly allocated to absorbable subcuticular sutures ( = 100), non-absorbable nylon sutures ( = 100) and surgical staplers ( = 100) for skin closure. Post-operative wound complications, pain, cosmetic appearance, closure time, and surgeon's and patient's satisfaction were recorded post-operatively on day 3, days 7-10 and at weeks 4-6. The primary outcome was rate of wound disruption among the women in three groups at three occasions. The secondary outcomes were wound infection rate, induration, swelling, cosmetic appearance, pain, surgeon's satisfaction, patient's satisfaction and closure time.

RESULTS

Significantly more women developed wound dehiscence in the stapler group ( = 0.039) at post-operative days 7-10 while in sub-group analysis, a similar outcome was seen between the other two groups ( = 0.999). The patient's and surgeon's satisfaction and cosmesis were maximum with absorbable subcutaneous monocryl sutures and minimum with stapler skin closure. Pain was maximum after non-absorbable nylon sutures, while application time was minimum in staplers application.

CONCLUSION

Present study suggests a benefit with sutures compared to surgical staplers in terms of wound dehiscence, infection, cosmesis and patient's satisfaction. Among the methods of skin closure, absorbable subcuticular monocryl and non-absorbable nylon sutures have similar outcomes with marginal benefit in absorbable subcuticular monocryl sutures.

摘要

背景

剖宫产与术后手术并发症相关,如伤口裂开、硬结和血肿。优化手术技术对于确保接受剖宫产的女性获得最佳手术效果至关重要。

方法

这是一项在三级护理中心进行的随机对照试验。共有300名首次接受剖宫产的女性被随机分配接受可吸收皮下缝线(n = 100)、不可吸收尼龙缝线(n = 100)和手术吻合器(n = 100)进行皮肤缝合。术后第3天、第7 - 10天以及第4 - 6周记录术后伤口并发症、疼痛、美观程度、缝合时间以及外科医生和患者的满意度。主要结局是三组女性在三个时间点的伤口裂开率。次要结局包括伤口感染率、硬结、肿胀、美观程度、疼痛、外科医生满意度、患者满意度和缝合时间。

结果

在术后第7 - 10天,吻合器组伤口裂开的女性明显更多(P = 0.039),而在亚组分析中,其他两组之间出现了类似的结果(P = 0.999)。患者和外科医生对可吸收皮下单丝缝线的满意度和美观程度最高,对吻合器皮肤缝合的满意度和美观程度最低。不可吸收尼龙缝线后的疼痛最严重,而吻合器应用的时间最短。

结论

本研究表明,在伤口裂开、感染、美观程度和患者满意度方面,与手术吻合器相比,缝线具有优势。在皮肤缝合方法中,可吸收皮下单丝缝线和不可吸收尼龙缝线的效果相似,可吸收皮下单丝缝线略有优势。

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本文引用的文献

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Cesarean section complications according to degree of emergency during labour.根据分娩时紧急程度划分的剖宫产并发症
Eur J Obstet Gynecol Reprod Biol. 2021 Jan;256:320-325. doi: 10.1016/j.ejogrb.2020.11.047. Epub 2020 Nov 16.
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Risks factors FOR wound complications after cesarean section.剖宫产术后伤口并发症的风险因素。
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