Goruntla Narayana, Ganzi Neelima, Otturu Mallika, Vaddi Sai Nikhitha, Mood Sree Lakshmi, Suchitra M Jyothi, Veerabhadrappa Kasturi Vishwanathasetty, Ezeonwumelu Joseph Obiezu Chukwujekwu, Bukke Sarad Pawar Naik
Department of Clinical Pharmacy and Pharmacy Practice, School of Pharmacy, Kampala International University, Western Campus, Ishaka, Uganda.
Department of Pharmacy Practice, JSS College of Pharmacy, JSSAHER, Mysuru, Karnataka India.
J Obstet Gynaecol India. 2025 Apr;75(Suppl 1):317-326. doi: 10.1007/s13224-024-01984-8. Epub 2024 May 2.
Medication (prescription or nonprescription) use during pregnancy is associated with a risk of harm to maternal and fetal health. Pregnant women's knowledge, attitude, and practice (KAP) toward safe medication use can influence positive outcomes. The study aims to assess and explore the risk factors associated with KAP toward medication use during pregnancy.
An interview-based, cross-sectional survey was conducted among pregnant women attending the obstetrics and gynecology department of a secondary care referral hospital. A predesigned, validated 24-item questionnaire was used to assess the KAP toward medication use among pregnant women. A binary logistic regression analysis was used to identify factors associated with the KAP levels of pregnant women.
A total of 300 pregnant women with a mean (SD) age of 24.6 (3.9) years have participated in this study. The study shows that the majority of pregnant women have good knowledge (75.33%), and a positive attitude (91.33%) toward safe medication use, but the rational practice is very low (35.00%). Factors, like advanced age, urban residence, higher education level, and healthcare job, were significantly positively associated with good knowledge and rational practice toward safe medication use during pregnancy with a < 0.05.
The study concludes that pregnant women have good knowledge, and positive attitudes toward safe medication use; still there is a wide gap in transforming this knowledge and behavior into real practice. So, to address the gap identified in the practice of pregnant women, a hospital or community-based sensitization program can be conducted targeting young age, rural residents, illiterates, and non-healthcare professional groups on medication safety during pregnancy.
孕期使用药物（处方药或非处方药）与危害母婴健康的风险相关。孕妇对安全用药的知识、态度和行为（KAP）会影响积极的结果。本研究旨在评估和探索与孕期用药KAP相关的风险因素。
在一家二级医疗转诊医院的妇产科就诊的孕妇中进行了一项基于访谈的横断面调查。使用一份预先设计并经过验证的包含24个条目的问卷来评估孕妇对用药的KAP。采用二元逻辑回归分析来确定与孕妇KAP水平相关的因素。
共有300名平均（标准差）年龄为24.6（3.9）岁的孕妇参与了本研究。研究表明，大多数孕妇对安全用药有良好的知识（75.33%）和积极的态度（91.33%），但合理用药行为非常低（35.00%）。年龄较大、居住在城市、教育水平较高和从事医疗保健工作等因素与孕期安全用药的良好知识和合理用药行为显著正相关，P < 0.05。
该研究得出结论，孕妇对安全用药有良好的知识和积极的态度；但将这些知识和行为转化为实际行动仍存在很大差距。因此，为解决孕妇实际行为中发现的差距，可以针对年轻年龄、农村居民、文盲和非医疗保健专业群体开展基于医院或社区的孕期用药安全宣传项目。
