Suppr超能文献

冠心病患者单核细胞与高密度脂蛋白比值与冠状动脉直径的研究。

Study of Monocyte-High Density Lipoprotein ratio to coronary artery diameter in coronary heart disease patients.

作者信息

Gani Azhari, Yusuf Muhammad Diah, Adewiyah Siti

机构信息

Department of Internal Medicine, Faculty of Medicine, Universitas Syiah Kuala and Dr. Zainal Abidin Hospital, Banda Aceh, Indonesia.

Internal Medicine Specialist Education Program, Faculty of Medicine, Universitas Syiah Kuala and Dr. Zainal Abidin Hospital, Banda Aceh, Indonesia.

出版信息

Glob Cardiol Sci Pract. 2025 Feb 28;2025(1):e202511. doi: 10.21542/gcsp.2025.11.

Abstract

BACKGROUND

The Monocyte to High-Density Lipoprotein Ratio (MHR) ratio reflects the proatherogenic and antiatherogenic balance and increased MHR values are related to coronary atherosclerosis obstruction's presence, progressivity, and severity. This study uses medical records and coronary angiography data to assess the correlation between MHR and coronary artery diameter in coronary heart disease patients.

METHODS

This study involved data from 230 patient medical records. The data collection approach was a cross-section design, and total sampling was performed by citing medical records of patients who underwent coronary angiography at the catheterization installation of Dr. Zainal Abidin Hospital, Banda Aceh, Indonesia.

RESULTS

The multivariate test showed that MHR and the coronary slow flow group, MINOCA, and stenosis were significant with a value of  < 0.0001. The results of the bivariate test showed the relationship between MHR and coronary artery diameter in all three groups. Coronary slow flow, MINOCA, and stenosis were insignificant  > 0.05.

CONCLUSION

This study shows that MHR can be a suitable, inexpensive, fast parameter for identifying the severity of coronary atherosclerosis obstruction.

摘要

背景

单核细胞与高密度脂蛋白比值(MHR)反映了促动脉粥样硬化和抗动脉粥样硬化的平衡,MHR值升高与冠状动脉粥样硬化阻塞的存在、进展和严重程度相关。本研究利用病历和冠状动脉造影数据评估冠心病患者中MHR与冠状动脉直径之间的相关性。

方法

本研究涉及230例患者病历数据。数据收集方法采用横断面设计,通过引用在印度尼西亚班达亚齐宰纳尔·阿比丁博士医院导管室接受冠状动脉造影的患者病历进行全样本抽样。

结果

多变量检验显示,MHR与冠状动脉慢血流组、心肌梗死伴非阻塞性冠状动脉病变(MINOCA)和狭窄具有显著相关性,P值<0.0001。双变量检验结果显示,在所有三组中MHR与冠状动脉直径之间存在关联。冠状动脉慢血流、MINOCA和狭窄无显著相关性,P>0.05。

结论

本研究表明,MHR可以作为一种合适、廉价、快速的参数来识别冠状动脉粥样硬化阻塞的严重程度。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d20c/12085926/839648704746/gcsp-2025-1-e202511-g001.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验