Gani Azhari, Yusuf Muhammad Diah, Adewiyah Siti
Department of Internal Medicine, Faculty of Medicine, Universitas Syiah Kuala and Dr. Zainal Abidin Hospital, Banda Aceh, Indonesia.
Internal Medicine Specialist Education Program, Faculty of Medicine, Universitas Syiah Kuala and Dr. Zainal Abidin Hospital, Banda Aceh, Indonesia.
Glob Cardiol Sci Pract. 2025 Feb 28;2025(1):e202511. doi: 10.21542/gcsp.2025.11.
The Monocyte to High-Density Lipoprotein Ratio (MHR) ratio reflects the proatherogenic and antiatherogenic balance and increased MHR values are related to coronary atherosclerosis obstruction's presence, progressivity, and severity. This study uses medical records and coronary angiography data to assess the correlation between MHR and coronary artery diameter in coronary heart disease patients.
This study involved data from 230 patient medical records. The data collection approach was a cross-section design, and total sampling was performed by citing medical records of patients who underwent coronary angiography at the catheterization installation of Dr. Zainal Abidin Hospital, Banda Aceh, Indonesia.
The multivariate test showed that MHR and the coronary slow flow group, MINOCA, and stenosis were significant with a value of < 0.0001. The results of the bivariate test showed the relationship between MHR and coronary artery diameter in all three groups. Coronary slow flow, MINOCA, and stenosis were insignificant > 0.05.
This study shows that MHR can be a suitable, inexpensive, fast parameter for identifying the severity of coronary atherosclerosis obstruction.
单核细胞与高密度脂蛋白比值（MHR）反映了促动脉粥样硬化和抗动脉粥样硬化的平衡，MHR值升高与冠状动脉粥样硬化阻塞的存在、进展和严重程度相关。本研究利用病历和冠状动脉造影数据评估冠心病患者中MHR与冠状动脉直径之间的相关性。
本研究涉及230例患者病历数据。数据收集方法采用横断面设计，通过引用在印度尼西亚班达亚齐宰纳尔·阿比丁博士医院导管室接受冠状动脉造影的患者病历进行全样本抽样。
多变量检验显示，MHR与冠状动脉慢血流组、心肌梗死伴非阻塞性冠状动脉病变（MINOCA）和狭窄具有显著相关性，P值<0.0001。双变量检验结果显示，在所有三组中MHR与冠状动脉直径之间存在关联。冠状动脉慢血流、MINOCA和狭窄无显著相关性，P>0.05。
本研究表明，MHR可以作为一种合适、廉价、快速的参数来识别冠状动脉粥样硬化阻塞的严重程度。
